KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHLPP2
All Species:
22.73
Human Site:
S1082
Identified Species:
62.5
UniProt:
Q6ZVD8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZVD8
NP_055835.2
1323
146751
S1082
G
I
A
S
E
F
S
S
E
M
S
T
S
E
V
Chimpanzee
Pan troglodytes
XP_511230
1382
153017
S1141
G
I
A
S
E
F
S
S
E
M
S
T
S
E
V
Rhesus Macaque
Macaca mulatta
XP_001105985
1323
146774
S1082
G
I
A
S
E
F
S
S
E
M
S
T
S
E
V
Dog
Lupus familis
XP_546844
1407
155894
S1166
G
I
A
S
E
F
G
S
E
M
S
T
S
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXA7
1320
145928
S1079
G
I
A
S
E
F
S
S
E
M
S
T
S
E
V
Rat
Rattus norvegicus
Q9WTR8
1696
183345
E1443
M
A
S
E
I
S
S
E
L
S
T
S
E
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509377
1323
146060
S1076
G
I
A
S
E
F
S
S
E
M
S
A
S
E
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394402
1147
128561
G924
N
K
A
H
N
G
S
G
R
Y
F
K
N
R
R
Nematode Worm
Caenorhab. elegans
Q09564
1036
117809
S813
R
I
N
G
V
I
G
S
S
R
Q
I
G
H
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
98.6
86.2
N.A.
90.6
41.3
N.A.
86
N.A.
N.A.
N.A.
N.A.
N.A.
23.4
25.7
N.A.
Protein Similarity:
100
95.1
99.2
89.9
N.A.
95
55.3
N.A.
92.8
N.A.
N.A.
N.A.
N.A.
N.A.
39.5
42.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
78
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
67
0
0
12
67
0
0
0
12
67
0
% E
% Phe:
0
0
0
0
0
67
0
0
0
0
12
0
0
0
12
% F
% Gly:
67
0
0
12
0
12
23
12
0
0
0
0
12
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
78
0
0
12
12
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
67
0
0
0
12
0
% M
% Asn:
12
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
12
0
0
0
12
12
% R
% Ser:
0
0
12
67
0
12
78
78
12
12
67
12
67
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
56
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _