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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT18 All Species: 29.7
Human Site: S139 Identified Species: 72.59
UniProt: Q6ZVK8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZVK8 NP_079091.3 323 35469 S139 S K E A D A E S L Q A A W Y P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001101711 323 35596 S139 S K E A D A E S L Q A A W Y P
Dog Lupus familis XP_851438 399 43955 S215 S K E A D A E S L Q A G W Y P
Cat Felis silvestris
Mouse Mus musculus Q3U2V3 323 35675 S139 S K D A D S E S L Q A G W Y P
Rat Rattus norvegicus Q641Y7 323 35628 S139 S K N A D S E S L Q A G W Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512510 321 35013 S137 L D E A D E E S L Q A G W Y P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q568Q0 325 36882 S136 T A E A D D E S L Q A H W W D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650083 340 37620 S154 P A D A D A E S I Q A R W V R
Honey Bee Apis mellifera XP_397372 323 36040 S148 L E E A N K E S L Q A C W I S
Nematode Worm Caenorhab. elegans O45830 365 41623 A172 E P D Q E S L A A E W Y N I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.9 71.9 N.A. 81.1 82 N.A. 68.7 N.A. N.A. 46.1 N.A. 35.8 34.3 30.6 N.A.
Protein Similarity: 100 N.A. 97.5 76.1 N.A. 90.7 91 N.A. 79.5 N.A. N.A. 64.6 N.A. 50.2 56.3 42.4 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 80 80 N.A. 73.3 N.A. N.A. 60 N.A. 53.3 53.3 0 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 86.6 N.A. 73.3 N.A. N.A. 73.3 N.A. 66.6 66.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 90 0 40 0 10 10 0 90 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 10 30 0 80 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 10 10 60 0 10 10 90 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 20 0 % I
% Lys: 0 50 0 0 0 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 20 0 0 0 0 0 10 0 80 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 60 % P
% Gln: 0 0 0 10 0 0 0 0 0 90 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % R
% Ser: 50 0 0 0 0 30 0 90 0 0 0 0 0 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 90 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _