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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD8
All Species:
6.36
Human Site:
S375
Identified Species:
14
UniProt:
Q6ZWB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWB6
NP_938167.1
473
52440
S375
T
P
Q
D
N
P
S
S
A
Q
Q
A
T
A
H
Chimpanzee
Pan troglodytes
XP_001137708
273
29563
R183
A
K
F
R
R
V
A
R
I
T
V
C
G
K
T
Rhesus Macaque
Macaca mulatta
XP_001099551
473
52469
S375
T
P
Q
D
N
P
S
S
A
Q
Q
A
T
A
H
Dog
Lupus familis
XP_544324
428
49116
Q336
I
C
G
P
V
T
R
Q
T
N
I
Q
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q50H33
476
52750
N378
T
P
Q
D
N
P
A
N
T
Q
Q
A
A
A
H
Rat
Rattus norvegicus
B1WC97
289
33074
I199
V
F
K
E
E
M
P
I
T
P
Y
E
C
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511503
885
96085
P790
Q
E
T
V
I
C
G
P
V
T
R
Q
S
N
I
Chicken
Gallus gallus
Q5ZJP7
289
33209
I199
V
F
K
E
E
M
P
I
T
P
Y
E
C
P
H
Frog
Xenopus laevis
NP_001088444
324
35845
A234
D
A
K
F
R
R
V
A
R
I
T
V
C
G
K
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
T146
I
I
T
Q
L
T
I
T
T
K
V
H
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794204
249
27757
S158
D
V
K
F
R
K
V
S
R
I
L
V
S
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.9
98.7
59.6
N.A.
94.9
23
N.A.
31.9
23.2
28.3
20.2
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
36.5
98.9
69.3
N.A.
96.6
34.2
N.A.
39.6
33.4
41.2
31.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
0
100
6.6
N.A.
73.3
0
N.A.
0
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
6.6
N.A.
86.6
13.3
N.A.
13.3
20
13.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
19
10
19
0
0
28
10
28
0
% A
% Cys:
0
10
0
0
0
10
0
0
0
0
0
10
28
0
0
% C
% Asp:
19
0
0
28
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
19
19
0
0
0
0
0
0
19
0
0
0
% E
% Phe:
0
19
10
19
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
0
0
10
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
37
% H
% Ile:
19
10
0
0
10
0
10
19
10
19
10
0
0
0
10
% I
% Lys:
0
10
37
0
0
10
0
0
0
10
0
0
0
10
19
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
10
0
0
19
19
% L
% Met:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
28
0
0
10
0
10
0
0
0
10
0
% N
% Pro:
0
28
0
10
0
28
19
10
0
19
0
0
0
19
0
% P
% Gln:
10
0
28
10
0
0
0
10
0
28
28
19
0
0
0
% Q
% Arg:
0
0
0
10
28
10
10
10
19
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
28
0
0
0
0
28
0
0
% S
% Thr:
28
0
19
0
0
19
0
10
46
19
10
0
28
0
10
% T
% Val:
19
10
0
10
10
10
19
0
10
0
19
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _