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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD8
All Species:
10
Human Site:
S418
Identified Species:
22
UniProt:
Q6ZWB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWB6
NP_938167.1
473
52440
S418
E
L
F
Q
T
L
I
S
K
S
R
E
T
N
L
Chimpanzee
Pan troglodytes
XP_001137708
273
29563
F224
R
Y
Y
L
K
F
N
F
L
E
Q
A
F
D
K
Rhesus Macaque
Macaca mulatta
XP_001099551
473
52469
S418
E
L
F
Q
T
L
I
S
K
S
R
E
T
N
L
Dog
Lupus familis
XP_544324
428
49116
N377
T
S
G
S
R
E
S
N
M
S
S
K
K
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q50H33
476
52750
S421
E
L
F
Q
S
L
I
S
K
S
R
E
T
N
L
Rat
Rattus norvegicus
B1WC97
289
33074
D240
G
P
W
E
A
V
A
D
V
Y
D
L
L
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511503
885
96085
S834
L
T
T
G
S
R
E
S
N
V
S
K
K
K
S
Chicken
Gallus gallus
Q5ZJP7
289
33209
D240
G
P
W
E
A
V
A
D
V
Y
D
L
L
H
C
Frog
Xenopus laevis
NP_001088444
324
35845
N275
S
R
Y
Y
L
K
F
N
F
L
E
Q
A
F
D
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
E187
G
P
C
D
Y
H
Q
E
V
S
L
R
V
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794204
249
27757
I200
A
R
F
Y
L
K
H
I
Y
L
E
Q
A
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.9
98.7
59.6
N.A.
94.9
23
N.A.
31.9
23.2
28.3
20.2
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
36.5
98.9
69.3
N.A.
96.6
34.2
N.A.
39.6
33.4
41.2
31.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
0
100
6.6
N.A.
93.3
0
N.A.
6.6
0
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
20
N.A.
100
26.6
N.A.
20
26.6
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
0
19
0
0
0
0
10
19
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
0
0
10
0
0
0
19
0
0
19
0
0
10
19
% D
% Glu:
28
0
0
19
0
10
10
10
0
10
19
28
0
0
0
% E
% Phe:
0
0
37
0
0
10
10
10
10
0
0
0
10
19
0
% F
% Gly:
28
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
28
0
% H
% Ile:
0
0
0
0
0
0
28
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
19
0
0
28
0
0
19
19
19
10
% K
% Leu:
10
28
0
10
19
28
0
0
10
19
10
19
19
0
37
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
19
10
0
0
0
0
28
0
% N
% Pro:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
28
0
0
10
0
0
0
10
19
0
0
0
% Q
% Arg:
10
19
0
0
10
10
0
0
0
0
28
10
0
0
0
% R
% Ser:
10
10
0
10
19
0
10
37
0
46
19
0
0
0
10
% S
% Thr:
10
10
10
0
19
0
0
0
0
0
0
0
28
0
0
% T
% Val:
0
0
0
0
0
19
0
0
28
10
0
0
10
0
0
% V
% Trp:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
19
19
10
0
0
0
10
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _