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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD8
All Species:
9.09
Human Site:
S426
Identified Species:
20
UniProt:
Q6ZWB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWB6
NP_938167.1
473
52440
S426
K
S
R
E
T
N
L
S
K
K
K
V
C
E
K
Chimpanzee
Pan troglodytes
XP_001137708
273
29563
L232
L
E
Q
A
F
D
K
L
S
E
S
G
F
H
M
Rhesus Macaque
Macaca mulatta
XP_001099551
473
52469
S426
K
S
R
E
T
N
L
S
K
K
K
V
C
E
K
Dog
Lupus familis
XP_544324
428
49116
V385
M
S
S
K
K
K
A
V
K
E
K
L
S
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q50H33
476
52750
S429
K
S
R
E
T
N
L
S
K
K
K
V
C
E
K
Rat
Rattus norvegicus
B1WC97
289
33074
L248
V
Y
D
L
L
H
C
L
V
T
D
L
S
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511503
885
96085
A842
N
V
S
K
K
K
S
A
K
E
K
L
S
I
E
Chicken
Gallus gallus
Q5ZJP7
289
33209
I248
V
Y
D
L
L
H
C
I
V
T
D
L
S
D
R
Frog
Xenopus laevis
NP_001088444
324
35845
K283
F
L
E
Q
A
F
D
K
L
S
E
S
G
F
H
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
M195
V
S
L
R
V
H
L
M
D
Y
I
T
K
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794204
249
27757
I208
Y
L
E
Q
A
F
D
I
L
A
G
S
G
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.9
98.7
59.6
N.A.
94.9
23
N.A.
31.9
23.2
28.3
20.2
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
36.5
98.9
69.3
N.A.
96.6
34.2
N.A.
39.6
33.4
41.2
31.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
0
100
20
N.A.
100
0
N.A.
13.3
0
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
46.6
N.A.
100
20
N.A.
46.6
26.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
0
10
10
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
28
0
0
% C
% Asp:
0
0
19
0
0
10
19
0
10
0
19
0
0
10
0
% D
% Glu:
0
10
19
28
0
0
0
0
0
28
10
0
0
28
19
% E
% Phe:
10
0
0
0
10
19
0
0
0
0
0
0
10
19
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
19
0
10
% G
% His:
0
0
0
0
0
28
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
19
0
0
10
0
0
19
0
% I
% Lys:
28
0
0
19
19
19
10
10
46
28
46
0
10
0
37
% K
% Leu:
10
19
10
19
19
0
37
19
19
0
0
37
0
0
0
% L
% Met:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
19
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
28
10
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
46
19
0
0
0
10
28
10
10
10
19
37
0
0
% S
% Thr:
0
0
0
0
28
0
0
0
0
19
0
10
0
0
0
% T
% Val:
28
10
0
0
10
0
0
10
19
0
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _