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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD8
All Species:
20
Human Site:
T251
Identified Species:
44
UniProt:
Q6ZWB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWB6
NP_938167.1
473
52440
T251
A
K
E
V
F
G
D
T
L
N
E
S
R
D
P
Chimpanzee
Pan troglodytes
XP_001137708
273
29563
S59
P
D
Y
F
P
E
R
S
R
L
Q
R
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001099551
473
52469
T251
A
K
E
V
F
G
D
T
L
N
E
S
R
D
P
Dog
Lupus familis
XP_544324
428
49116
S212
F
G
E
T
L
N
E
S
R
D
P
D
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q50H33
476
52750
T254
A
K
E
V
F
G
D
T
L
N
E
S
R
D
P
Rat
Rattus norvegicus
B1WC97
289
33074
T75
T
L
R
R
Y
E
D
T
M
L
A
A
M
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511503
885
96085
T666
A
K
E
V
F
G
E
T
L
N
E
S
R
D
P
Chicken
Gallus gallus
Q5ZJP7
289
33209
T75
T
L
R
R
Y
E
D
T
M
L
A
A
M
F
S
Frog
Xenopus laevis
NP_001088444
324
35845
R110
D
Y
F
P
E
R
S
R
L
Q
R
E
A
E
H
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
L22
T
L
N
V
G
G
H
L
Y
T
T
S
I
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794204
249
27757
S34
T
L
T
K
D
R
D
S
L
L
A
E
I
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.9
98.7
59.6
N.A.
94.9
23
N.A.
31.9
23.2
28.3
20.2
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
36.5
98.9
69.3
N.A.
96.6
34.2
N.A.
39.6
33.4
41.2
31.7
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
100
0
100
20
N.A.
100
13.3
N.A.
93.3
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
40
N.A.
100
33.3
N.A.
100
33.3
13.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
0
0
0
0
0
0
0
28
19
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
55
0
0
10
0
10
0
37
0
% D
% Glu:
0
0
46
0
10
28
19
0
0
0
37
19
10
10
10
% E
% Phe:
10
0
10
10
37
0
0
0
0
0
0
0
0
28
0
% F
% Gly:
0
10
0
0
10
46
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
37
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
37
0
0
10
0
0
10
55
37
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
19
0
0
0
19
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
37
0
0
0
0
0
% N
% Pro:
10
0
0
10
10
0
0
0
0
0
10
0
0
0
46
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
19
19
0
19
10
10
19
0
10
10
46
0
0
% R
% Ser:
0
0
0
0
0
0
10
28
0
0
0
46
0
10
19
% S
% Thr:
37
0
10
10
0
0
0
55
0
10
10
0
0
0
19
% T
% Val:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
19
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _