KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK10
All Species:
1.52
Human Site:
S860
Identified Species:
5.56
UniProt:
Q6ZWH5
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWH5
NP_955379.2
1172
133229
S860
L
K
S
E
L
S
E
S
A
D
L
P
P
E
G
Chimpanzee
Pan troglodytes
XP_001165180
1008
114510
A724
G
C
I
L
Y
Q
M
A
T
L
S
P
P
F
Y
Rhesus Macaque
Macaca mulatta
XP_001094156
1008
114328
A724
G
C
I
L
Y
Q
M
A
T
L
N
P
P
F
Y
Dog
Lupus familis
XP_542757
1007
114414
A723
G
C
I
L
Y
Q
M
A
T
L
N
P
P
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGM2
1111
126039
H827
N
R
N
A
V
T
C
H
H
E
L
A
L
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507433
630
71398
L346
H
S
D
H
L
K
L
L
W
S
V
V
W
I
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P84199
981
111633
T697
D
D
L
R
F
L
I
T
S
C
L
A
P
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.8
83.4
81.6
N.A.
84.8
N.A.
N.A.
42
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
N.A.
Protein Similarity:
100
85.1
84.6
83.6
N.A.
89.2
N.A.
N.A.
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.2
N.A.
P-Site Identity:
100
13.3
13.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
20
20
N.A.
40
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
43
15
0
0
29
0
0
0
% A
% Cys:
0
43
0
0
0
0
15
0
0
15
0
0
0
0
0
% C
% Asp:
15
15
15
0
0
0
0
0
0
15
0
0
0
15
0
% D
% Glu:
0
0
0
15
0
0
15
0
0
15
0
0
0
15
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
43
0
% F
% Gly:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% G
% His:
15
0
0
15
0
0
0
15
15
0
0
0
0
0
0
% H
% Ile:
0
0
43
0
0
0
15
0
0
0
0
0
0
15
0
% I
% Lys:
0
15
0
0
0
15
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
15
43
29
15
15
15
0
43
43
0
15
15
15
% L
% Met:
0
0
0
0
0
0
43
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
15
0
0
0
0
0
0
0
29
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
58
72
0
15
% P
% Gln:
0
0
0
0
0
43
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
15
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
15
0
0
15
0
15
15
15
15
0
0
0
15
% S
% Thr:
0
0
0
0
0
15
0
15
43
0
0
0
0
0
0
% T
% Val:
0
0
0
0
15
0
0
0
0
0
15
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
15
0
0
0
15
0
0
% W
% Tyr:
0
0
0
0
43
0
0
0
0
0
0
0
0
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _