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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMPRSS11F
All Species:
20
Human Site:
Y61
Identified Species:
62.86
UniProt:
Q6ZWK6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWK6
NP_997290.2
438
49410
Y61
E
D
D
K
S
F
Y
Y
L
A
S
F
K
V
T
Chimpanzee
Pan troglodytes
XP_526606
417
47144
Y49
V
F
D
Q
K
K
E
Y
Y
H
G
S
F
K
I
Rhesus Macaque
Macaca mulatta
XP_001098667
447
50685
Y70
E
D
D
K
S
F
Y
Y
L
A
S
F
K
V
T
Dog
Lupus familis
XP_539293
448
50603
Y71
E
D
D
K
S
F
Y
Y
L
A
S
F
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHM9
439
49758
Y62
E
D
D
K
S
F
Y
Y
L
A
S
F
Q
V
T
Rat
Rattus norvegicus
Q6IE14
420
47224
Y52
V
E
N
K
I
Y
Y
Y
Q
G
S
F
K
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507588
345
37988
Chicken
Gallus gallus
XP_001234738
506
56860
Y130
Y
D
Q
K
L
F
Y
Y
S
G
N
I
K
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
93.7
87.2
N.A.
86.7
41.3
N.A.
55.4
38.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.6
95.9
92.6
N.A.
93.6
60.2
N.A.
67.3
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
46.6
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
66.6
N.A.
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
63
63
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
13
0
0
0
0
13
0
0
0
0
0
13
0
0
% E
% Phe:
0
13
0
0
0
63
0
0
0
0
0
63
13
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
25
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
13
0
13
13
% I
% Lys:
0
0
0
75
13
13
0
0
0
0
0
0
50
13
0
% K
% Leu:
0
0
0
0
13
0
0
0
50
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
13
13
0
0
0
0
13
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
0
0
0
13
0
63
13
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% T
% Val:
25
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
13
75
88
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _