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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4V2 All Species: 34.24
Human Site: S121 Identified Species: 68.48
UniProt: Q6ZWL3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZWL3 NP_997235.3 525 60724 S121 S S K Q I D K S S M Y K F L E
Chimpanzee Pan troglodytes XP_001165629 525 60693 S121 S S K Q I D K S S M Y K F L E
Rhesus Macaque Macaca mulatta XP_001088961 525 60830 S121 S S K Q I D K S S M Y K F L E
Dog Lupus familis XP_849364 575 66310 S171 S S R Q I D K S Y V Y K F L E
Cat Felis silvestris
Mouse Mus musculus Q9DBW0 525 60920 S121 S S K Q I D K S F L Y K F L Q
Rat Rattus norvegicus A2RRT9 525 60562 S121 S S K Q I D K S F M Y K F L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001001879 530 61513 S122 S S K H I K K S F L Y T F L H
Frog Xenopus laevis NP_001086053 522 60293 S115 T S K H M D K S Y A Y K F L H
Zebra Danio Brachydanio rerio NP_001073465 510 58788 S114 N S R H L D K S Y S Y R F L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA27 535 60739 S129 S Q K F V N K S H D Y D Y L H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500637 495 56760 G103 S T K H L N K G F A Y V L L E
Sea Urchin Strong. purpuratus XP_786946 473 53963 F98 A N W G Q K W F H R R K M L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.7 72.3 N.A. 81.9 83.4 N.A. N.A. 61.5 61.9 62.2 N.A. 47 N.A. 42.4 46.6
Protein Similarity: 100 99.8 98.6 82.7 N.A. 92 92.5 N.A. N.A. 78.4 76.9 77.9 N.A. 65.9 N.A. 63.2 59.4
P-Site Identity: 100 100 100 80 N.A. 80 86.6 N.A. N.A. 60 60 46.6 N.A. 40 N.A. 40 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 73.3 N.A. 60 N.A. 60 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 67 0 0 0 9 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42 % E
% Phe: 0 0 0 9 0 0 0 9 34 0 0 0 75 0 0 % F
% Gly: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 34 0 0 0 0 17 0 0 0 0 0 34 % H
% Ile: 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 75 0 0 17 92 0 0 0 0 67 0 0 0 % K
% Leu: 0 0 0 0 17 0 0 0 0 17 0 0 9 100 0 % L
% Met: 0 0 0 0 9 0 0 0 0 34 0 0 9 0 0 % M
% Asn: 9 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 50 9 0 0 0 0 0 0 0 0 0 17 % Q
% Arg: 0 0 17 0 0 0 0 0 0 9 9 9 0 0 0 % R
% Ser: 75 75 0 0 0 0 0 84 25 9 0 0 0 0 0 % S
% Thr: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 9 % T
% Val: 0 0 0 0 9 0 0 0 0 9 0 9 0 0 0 % V
% Trp: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 25 0 92 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _