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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4V2 All Species: 30.91
Human Site: S347 Identified Species: 61.82
UniProt: Q6ZWL3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZWL3 NP_997235.3 525 60724 S347 W S L Y L L G S N P E V Q K K
Chimpanzee Pan troglodytes XP_001165629 525 60693 S347 W S L Y L L G S N P E V Q K K
Rhesus Macaque Macaca mulatta XP_001088961 525 60830 S347 W S L Y L L G S N P E V Q K K
Dog Lupus familis XP_849364 575 66310 S397 W S L Y L L G S Y P E V Q K Q
Cat Felis silvestris
Mouse Mus musculus Q9DBW0 525 60920 T347 W S L Y L L G T N P E V Q R K
Rat Rattus norvegicus A2RRT9 525 60562 S347 W S L Y L L G S N P E V Q R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001001879 530 61513 H351 W V L Y L L G H H P E A Q K K
Frog Xenopus laevis NP_001086053 522 60293 S343 W S L F L L G S H P E A Q R Q
Zebra Danio Brachydanio rerio NP_001073465 510 58788 S335 W A L H L I G S H P E V Q K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA27 535 60739 C360 W T L F L L G C H P E Y Q E R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500637 495 56760 P319 I H L L G N H P E V Q R K V Q
Sea Urchin Strong. purpuratus XP_786946 473 53963 H298 W A I L L I G H H P D V Q A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.7 72.3 N.A. 81.9 83.4 N.A. N.A. 61.5 61.9 62.2 N.A. 47 N.A. 42.4 46.6
Protein Similarity: 100 99.8 98.6 82.7 N.A. 92 92.5 N.A. N.A. 78.4 76.9 77.9 N.A. 65.9 N.A. 63.2 59.4
P-Site Identity: 100 100 100 86.6 N.A. 86.6 93.3 N.A. N.A. 73.3 66.6 66.6 N.A. 53.3 N.A. 6.6 40
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 80 93.3 93.3 N.A. 86.6 N.A. 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 0 0 0 0 0 17 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 84 0 0 9 0 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 92 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 9 0 0 9 17 42 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 0 17 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 50 50 % K
% Leu: 0 0 92 17 92 75 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 42 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 92 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 92 0 25 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 25 17 % R
% Ser: 0 59 0 0 0 0 0 59 0 0 0 0 0 0 0 % S
% Thr: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 0 0 0 9 0 67 0 9 0 % V
% Trp: 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 59 0 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _