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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4V2 All Species: 37.27
Human Site: Y124 Identified Species: 74.55
UniProt: Q6ZWL3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZWL3 NP_997235.3 525 60724 Y124 Q I D K S S M Y K F L E P W L
Chimpanzee Pan troglodytes XP_001165629 525 60693 Y124 Q I D K S S M Y K F L E P W L
Rhesus Macaque Macaca mulatta XP_001088961 525 60830 Y124 Q I D K S S M Y K F L E P W L
Dog Lupus familis XP_849364 575 66310 Y174 Q I D K S Y V Y K F L E P W L
Cat Felis silvestris
Mouse Mus musculus Q9DBW0 525 60920 Y124 Q I D K S F L Y K F L Q P W L
Rat Rattus norvegicus A2RRT9 525 60562 Y124 Q I D K S F M Y K F L Q P W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001001879 530 61513 Y125 H I K K S F L Y T F L H P W L
Frog Xenopus laevis NP_001086053 522 60293 Y118 H M D K S Y A Y K F L H P W L
Zebra Danio Brachydanio rerio NP_001073465 510 58788 Y117 H L D K S Y S Y R F L H P W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA27 535 60739 Y132 F V N K S H D Y D Y L H P W L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500637 495 56760 Y106 H L N K G F A Y V L L E P W L
Sea Urchin Strong. purpuratus XP_786946 473 53963 R101 G Q K W F H R R K M L T P T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.7 72.3 N.A. 81.9 83.4 N.A. N.A. 61.5 61.9 62.2 N.A. 47 N.A. 42.4 46.6
Protein Similarity: 100 99.8 98.6 82.7 N.A. 92 92.5 N.A. N.A. 78.4 76.9 77.9 N.A. 65.9 N.A. 63.2 59.4
P-Site Identity: 100 100 100 86.6 N.A. 80 86.6 N.A. N.A. 60 66.6 60 N.A. 46.6 N.A. 46.6 20
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 73.3 N.A. 66.6 N.A. 60 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 0 9 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % E
% Phe: 9 0 0 0 9 34 0 0 0 75 0 0 0 0 9 % F
% Gly: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 34 0 0 0 0 17 0 0 0 0 0 34 0 0 0 % H
% Ile: 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 92 0 0 0 0 67 0 0 0 0 0 0 % K
% Leu: 0 17 0 0 0 0 17 0 0 9 100 0 0 0 92 % L
% Met: 0 9 0 0 0 0 34 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % P
% Gln: 50 9 0 0 0 0 0 0 0 0 0 17 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 84 25 9 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 9 0 9 0 % T
% Val: 0 9 0 0 0 0 9 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 92 0 % W
% Tyr: 0 0 0 0 0 25 0 92 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _