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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4V2
All Species:
39.09
Human Site:
Y224
Identified Species:
78.18
UniProt:
Q6ZWL3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWL3
NP_997235.3
525
60724
Y224
S
E
Y
V
R
A
V
Y
R
M
S
E
M
I
F
Chimpanzee
Pan troglodytes
XP_001165629
525
60693
Y224
S
E
Y
V
R
A
V
Y
R
M
S
E
M
I
F
Rhesus Macaque
Macaca mulatta
XP_001088961
525
60830
Y224
S
E
Y
V
R
A
V
Y
R
M
S
E
M
I
F
Dog
Lupus familis
XP_849364
575
66310
Y274
S
E
Y
V
R
A
I
Y
R
M
S
D
T
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBW0
525
60920
Y224
S
E
Y
V
R
T
V
Y
R
M
S
D
M
I
Y
Rat
Rattus norvegicus
A2RRT9
525
60562
Y224
S
E
Y
V
R
T
V
Y
R
M
S
D
M
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001879
530
61513
Y225
S
E
Y
V
R
A
V
Y
R
M
S
D
L
I
Q
Frog
Xenopus laevis
NP_001086053
522
60293
Y218
S
E
Y
V
Q
A
I
Y
K
M
S
D
I
I
Q
Zebra Danio
Brachydanio rerio
NP_001073465
510
58788
Y217
S
E
Y
V
Q
S
V
Y
K
M
S
D
I
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA27
535
60739
Y232
S
E
Y
V
K
A
V
Y
G
I
G
S
I
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500637
495
56760
H206
N
E
Y
V
W
A
V
H
T
I
N
K
L
I
S
Sea Urchin
Strong. purpuratus
XP_786946
473
53963
S182
V
K
A
V
G
R
M
S
E
L
V
T
I
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
72.3
N.A.
81.9
83.4
N.A.
N.A.
61.5
61.9
62.2
N.A.
47
N.A.
42.4
46.6
Protein Similarity:
100
99.8
98.6
82.7
N.A.
92
92.5
N.A.
N.A.
78.4
76.9
77.9
N.A.
65.9
N.A.
63.2
59.4
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
N.A.
80
60
60
N.A.
46.6
N.A.
40
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
73.3
N.A.
80
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
67
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% D
% Glu:
0
92
0
0
0
0
0
0
9
0
0
25
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% F
% Gly:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
17
0
0
17
0
0
34
84
0
% I
% Lys:
0
9
0
0
9
0
0
0
17
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
75
0
0
42
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
0
0
0
59
9
0
0
59
0
0
0
0
9
0
% R
% Ser:
84
0
0
0
0
9
0
9
0
0
75
9
0
0
9
% S
% Thr:
0
0
0
0
0
17
0
0
9
0
0
9
9
0
9
% T
% Val:
9
0
0
100
0
0
75
0
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
92
0
0
0
0
84
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _