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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4V2
All Species:
25.45
Human Site:
Y80
Identified Species:
50.91
UniProt:
Q6ZWL3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZWL3
NP_997235.3
525
60724
Y80
F
F
Q
Q
I
I
E
Y
T
E
E
Y
R
H
M
Chimpanzee
Pan troglodytes
XP_001165629
525
60693
Y80
F
F
Q
Q
I
I
E
Y
T
E
E
Y
R
H
M
Rhesus Macaque
Macaca mulatta
XP_001088961
525
60830
Y80
F
F
Q
Q
I
I
E
Y
T
E
E
Y
R
H
M
Dog
Lupus familis
XP_849364
575
66310
Y130
F
F
Q
Q
V
I
L
Y
S
E
E
S
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBW0
525
60920
Y80
F
F
Q
Q
L
I
Y
Y
T
E
E
F
R
H
L
Rat
Rattus norvegicus
A2RRT9
525
60562
Y80
F
F
Q
Q
I
I
Q
Y
T
E
E
F
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001879
530
61513
Y81
F
F
K
Q
L
Q
Q
Y
A
D
E
F
R
K
M
Frog
Xenopus laevis
NP_001086053
522
60293
F74
F
F
L
Q
M
C
E
F
T
E
L
F
R
V
E
Zebra Danio
Brachydanio rerio
NP_001073465
510
58788
G73
F
F
N
Q
I
I
E
G
T
N
E
N
R
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA27
535
60739
H77
A
I
E
M
N
V
D
H
D
E
L
F
N
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500637
495
56760
M62
F
M
N
Q
V
I
G
M
G
Y
L
Y
P
D
P
Sea Urchin
Strong. purpuratus
XP_786946
473
53963
M61
Q
R
E
F
F
V
D
M
T
T
L
M
E
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
72.3
N.A.
81.9
83.4
N.A.
N.A.
61.5
61.9
62.2
N.A.
47
N.A.
42.4
46.6
Protein Similarity:
100
99.8
98.6
82.7
N.A.
92
92.5
N.A.
N.A.
78.4
76.9
77.9
N.A.
65.9
N.A.
63.2
59.4
P-Site Identity:
100
100
100
66.6
N.A.
73.3
80
N.A.
N.A.
46.6
46.6
66.6
N.A.
6.6
N.A.
26.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
100
N.A.
N.A.
80
66.6
73.3
N.A.
46.6
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
9
9
0
0
0
9
0
% D
% Glu:
0
0
17
0
0
0
42
0
0
67
67
0
9
9
9
% E
% Phe:
84
75
0
9
9
0
0
9
0
0
0
42
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
59
0
% H
% Ile:
0
9
0
0
42
67
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
9
0
17
0
9
0
0
0
34
0
0
0
34
% L
% Met:
0
9
0
9
9
0
0
17
0
0
0
9
0
0
34
% M
% Asn:
0
0
17
0
9
0
0
0
0
9
0
9
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
9
0
50
84
0
9
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
75
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
67
9
0
0
0
0
0
% T
% Val:
0
0
0
0
17
17
0
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
59
0
9
0
34
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _