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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC3
All Species:
4.55
Human Site:
T398
Identified Species:
11.11
UniProt:
Q6ZXV5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZXV5
NP_861448.2
915
104009
T398
H
G
W
Q
K
I
S
T
K
S
V
F
K
K
L
Chimpanzee
Pan troglodytes
XP_522486
914
103832
T398
H
G
W
Q
K
I
S
T
K
S
V
F
K
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532644
915
103928
N398
H
G
W
Q
K
I
S
N
K
S
V
L
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH0
920
104179
N403
H
G
W
Q
K
I
S
N
K
S
V
L
K
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCD5
836
94386
A408
L
I
V
P
F
V
P
A
S
N
L
F
F
Y
V
Zebra Danio
Brachydanio rerio
XP_001922486
906
102514
Q398
Y
G
F
K
L
L
S
Q
K
G
G
L
K
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
R464
Y
G
F
E
Q
L
Q
R
R
G
S
L
S
W
Q
Honey Bee
Apis mellifera
XP_393964
996
112258
C399
G
Y
G
W
S
I
L
C
D
K
K
F
K
K
L
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
N276
S
K
F
Y
R
M
I
N
Y
T
Y
I
W
L
Y
Sea Urchin
Strong. purpuratus
XP_797370
844
95271
A405
I
A
M
E
R
L
Q
A
N
R
P
M
R
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.8
N.A.
89.7
N.A.
N.A.
N.A.
N.A.
26
73
N.A.
51.2
47.9
28.2
47.3
Protein Similarity:
100
99.7
N.A.
97.1
N.A.
94.6
N.A.
N.A.
N.A.
N.A.
43.2
85.9
N.A.
66.7
63.9
45.2
65.6
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
6.6
33.3
N.A.
6.6
33.3
0
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
33.3
66.6
N.A.
46.6
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
30
0
10
0
0
0
0
0
0
40
10
0
0
% F
% Gly:
10
60
10
0
0
0
0
0
0
20
10
0
0
0
0
% G
% His:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
50
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
10
40
0
0
0
50
10
10
0
60
60
0
% K
% Leu:
10
0
0
0
10
30
10
0
0
0
10
40
0
10
50
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
30
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
40
10
0
20
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
20
0
0
10
10
10
0
0
10
0
0
% R
% Ser:
10
0
0
0
10
0
50
0
10
40
10
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
0
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
40
0
0
0
20
% V
% Trp:
0
0
40
10
0
0
0
0
0
0
0
0
10
10
0
% W
% Tyr:
20
10
0
10
0
0
0
0
10
0
10
0
0
20
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _