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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC3
All Species:
6.06
Human Site:
T862
Identified Species:
14.81
UniProt:
Q6ZXV5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZXV5
NP_861448.2
915
104009
T862
R
Q
T
Q
I
V
K
T
S
D
N
K
S
Q
S
Chimpanzee
Pan troglodytes
XP_522486
914
103832
T861
R
Q
T
Q
I
V
K
T
S
D
N
K
S
Q
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532644
915
103928
P862
R
P
T
Q
I
I
K
P
S
D
N
K
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH0
920
104179
L866
E
S
R
P
P
Q
I
L
K
T
N
N
N
R
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCD5
836
94386
N801
K
L
E
E
A
E
Y
N
Y
L
R
A
L
Q
L
Zebra Danio
Brachydanio rerio
XP_001922486
906
102514
Q861
T
E
N
Q
G
H
G
Q
S
E
K
L
D
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
L892
R
L
Q
K
I
N
K
L
P
E
S
A
P
E
R
Honey Bee
Apis mellifera
XP_393964
996
112258
G862
N
S
I
G
S
T
S
G
T
S
G
L
N
N
M
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
S657
S
R
H
K
E
A
E
S
Q
Y
R
I
V
L
A
Sea Urchin
Strong. purpuratus
XP_797370
844
95271
R807
C
L
L
D
V
L
E
R
A
P
H
A
E
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.8
N.A.
89.7
N.A.
N.A.
N.A.
N.A.
26
73
N.A.
51.2
47.9
28.2
47.3
Protein Similarity:
100
99.7
N.A.
97.1
N.A.
94.6
N.A.
N.A.
N.A.
N.A.
43.2
85.9
N.A.
66.7
63.9
45.2
65.6
P-Site Identity:
100
100
N.A.
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
13.3
N.A.
20
0
0
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
46.6
13.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
10
0
0
30
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
30
0
0
10
0
0
% D
% Glu:
10
10
10
10
10
10
20
0
0
20
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
10
0
10
10
0
0
10
0
0
0
10
% G
% His:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
40
10
10
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
0
20
0
0
40
0
10
0
10
30
0
0
0
% K
% Leu:
0
30
10
0
0
10
0
20
0
10
0
20
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
10
0
0
10
0
10
0
0
40
10
20
10
10
% N
% Pro:
0
10
0
10
10
0
0
10
10
10
0
0
10
0
0
% P
% Gln:
0
20
10
40
0
10
0
10
10
0
0
0
0
40
0
% Q
% Arg:
40
10
10
0
0
0
0
10
0
0
20
0
0
10
10
% R
% Ser:
10
20
0
0
10
0
10
10
40
10
10
0
30
0
30
% S
% Thr:
10
0
30
0
0
10
0
20
10
10
0
0
0
10
0
% T
% Val:
0
0
0
0
10
20
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _