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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC3
All Species:
24.55
Human Site:
Y490
Identified Species:
60
UniProt:
Q6ZXV5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZXV5
NP_861448.2
915
104009
Y490
H
M
N
V
G
R
T
Y
K
N
L
N
R
T
K
Chimpanzee
Pan troglodytes
XP_522486
914
103832
Y490
H
M
N
V
G
R
T
Y
K
N
L
N
R
T
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532644
915
103928
Y490
H
M
N
V
G
R
T
Y
K
N
L
N
R
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH0
920
104179
Y495
H
M
N
V
G
R
T
Y
K
N
L
N
R
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCD5
836
94386
I488
E
M
L
Y
R
S
G
I
K
V
N
P
A
K
A
Zebra Danio
Brachydanio rerio
XP_001922486
906
102514
Y490
H
M
N
V
G
R
T
Y
K
N
L
N
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
F558
H
I
N
V
G
R
T
F
N
N
L
K
R
Y
A
Honey Bee
Apis mellifera
XP_393964
996
112258
Y491
H
I
N
V
G
R
T
Y
N
H
L
K
M
F
K
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
A351
G
I
I
S
F
L
P
A
S
N
I
F
F
T
V
Sea Urchin
Strong. purpuratus
XP_797370
844
95271
Y497
W
I
N
V
G
R
T
Y
R
Q
L
G
K
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.8
N.A.
89.7
N.A.
N.A.
N.A.
N.A.
26
73
N.A.
51.2
47.9
28.2
47.3
Protein Similarity:
100
99.7
N.A.
97.1
N.A.
94.6
N.A.
N.A.
N.A.
N.A.
43.2
85.9
N.A.
66.7
63.9
45.2
65.6
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
86.6
N.A.
60
60
13.3
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
100
N.A.
73.3
73.3
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
10
10
10
0
% F
% Gly:
10
0
0
0
80
0
10
0
0
0
0
10
0
0
0
% G
% His:
70
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
40
10
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
60
0
0
20
10
10
40
% K
% Leu:
0
0
10
0
0
10
0
0
0
0
80
0
0
0
0
% L
% Met:
0
60
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
80
0
0
0
0
0
20
70
10
50
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
80
0
0
10
0
0
0
60
0
20
% R
% Ser:
0
0
0
10
0
10
0
0
10
0
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
80
0
0
0
0
0
0
40
0
% T
% Val:
0
0
0
80
0
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
70
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _