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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP49
All Species:
13.64
Human Site:
S559
Identified Species:
30
UniProt:
Q70CQ1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70CQ1
NP_061031.2
688
79198
S559
H
L
K
R
F
R
W
S
G
R
N
H
R
E
K
Chimpanzee
Pan troglodytes
XP_518467
759
87316
S630
H
L
K
R
F
R
W
S
G
R
N
H
R
E
K
Rhesus Macaque
Macaca mulatta
XP_001085246
657
75261
N527
N
S
K
R
R
K
S
N
P
K
P
L
V
L
S
Dog
Lupus familis
XP_532134
681
77708
S552
H
L
K
R
F
R
W
S
G
R
N
H
R
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9L4
685
78254
S556
H
L
K
R
F
R
W
S
G
R
N
H
R
E
K
Rat
Rattus norvegicus
B2GUX4
565
62681
R441
A
P
V
C
D
R
C
R
Q
K
T
R
S
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510004
1411
160789
F643
T
I
E
R
P
S
K
F
M
K
S
E
E
Q
K
Chicken
Gallus gallus
O57429
357
40913
A233
P
T
C
C
R
C
K
A
R
T
R
C
T
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392160
541
61414
W417
Q
R
S
T
K
R
F
W
I
H
R
L
P
N
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792596
510
58338
V386
K
C
K
D
P
R
K
V
T
N
N
Y
P
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
K347
N
S
T
Q
D
A
I
K
Q
L
G
I
H
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.6
92.1
N.A.
90.4
22.9
N.A.
31.1
20.9
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
25.5
Protein Similarity:
100
90.5
92
93.9
N.A.
94.1
38
N.A.
38.5
32.4
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
40.1
P-Site Identity:
100
100
13.3
100
N.A.
100
13.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
40
100
N.A.
100
20
N.A.
46.6
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
10
10
19
0
10
10
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
10
10
37
0
% E
% Phe:
0
0
0
0
37
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
37
0
10
0
0
0
0
% G
% His:
37
0
0
0
0
0
0
0
0
10
0
37
10
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
10
0
0
10
0
0
0
% I
% Lys:
10
0
55
0
10
10
28
10
0
28
0
0
0
19
64
% K
% Leu:
0
37
0
0
0
0
0
0
0
10
0
19
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
10
0
10
46
0
0
10
0
% N
% Pro:
10
10
0
0
19
0
0
0
10
0
10
0
19
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
19
0
0
0
0
10
0
% Q
% Arg:
0
10
0
55
19
64
0
10
10
37
19
10
37
0
0
% R
% Ser:
0
19
10
0
0
10
10
37
0
0
10
0
10
0
10
% S
% Thr:
10
10
10
10
0
0
0
0
10
10
10
0
10
10
0
% T
% Val:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
37
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _