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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAPH1 All Species: 5.76
Human Site: S1066 Identified Species: 14.07
UniProt: Q70E73 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70E73 NP_976241.1 1250 135256 S1066 D S V V E F P S P P S D S D F
Chimpanzee Pan troglodytes XP_516044 1252 135697 S1068 D S M V E F P S P P S D S D F
Rhesus Macaque Macaca mulatta XP_001101993 662 72668 L480 A H S V S A V L Q E A Q R H A
Dog Lupus familis XP_545607 979 108307 S797 V E F P S P P S D S D F P P P
Cat Felis silvestris
Mouse Mus musculus Q8R5A3 670 74301 E488 S A G P P L Q E A Q T Q I E T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509550 268 31003 K86 L W L K D D G K K S W K K R Y
Chicken Gallus gallus Q5ZL23 485 54730 V303 E S F C G A S V I V P E L E G
Frog Xenopus laevis Q6DCV1 653 72662 K471 G E A N K Q E K K S S E V N K
Zebra Danio Brachydanio rerio Q6PFT9 646 70983 S464 K V P S N Q S S L P P P P P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797256 1407 155923 M1206 P P M S P K P M S P R P M V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 31.3 70.5 N.A. 31 N.A. N.A. 20.3 23.8 30.4 32.2 N.A. N.A. N.A. N.A. 26.1
Protein Similarity: 100 97.9 40.1 72 N.A. 40 N.A. N.A. 20.9 30.7 39.1 40.9 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 93.3 6.6 13.3 N.A. 0 N.A. N.A. 0 6.6 6.6 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 13.3 13.3 N.A. 20 N.A. N.A. 20 26.6 26.6 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 20 0 0 10 0 10 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 10 10 0 0 10 0 10 20 0 20 0 % D
% Glu: 10 20 0 0 20 0 10 10 0 10 0 20 0 20 0 % E
% Phe: 0 0 20 0 0 20 0 0 0 0 0 10 0 0 20 % F
% Gly: 10 0 10 0 10 0 10 0 0 0 0 0 0 0 10 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 10 0 0 10 10 10 0 20 20 0 0 10 10 0 10 % K
% Leu: 10 0 10 0 0 10 0 10 10 0 0 0 10 0 0 % L
% Met: 0 0 20 0 0 0 0 10 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 10 10 10 20 20 10 40 0 20 40 20 20 20 20 10 % P
% Gln: 0 0 0 0 0 20 10 0 10 10 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 10 10 0 % R
% Ser: 10 30 10 20 20 0 20 40 10 30 30 0 20 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 10 10 10 30 0 0 10 10 0 10 0 0 10 10 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _