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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP53
All Species:
9.39
Human Site:
T869
Identified Species:
22.96
UniProt:
Q70EK8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EK8
NP_061923.2
1073
120806
T869
L
W
S
S
H
L
R
T
V
G
L
K
P
E
T
Chimpanzee
Pan troglodytes
XP_517410
1073
120810
T869
L
W
S
S
H
L
R
T
V
R
L
K
P
E
T
Rhesus Macaque
Macaca mulatta
XP_001098826
1073
120920
T869
L
W
S
S
H
L
R
T
V
G
L
K
P
A
T
Dog
Lupus familis
XP_545046
1164
130992
M923
P
S
L
W
S
S
H
M
R
P
V
G
L
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P15975
1069
119237
G866
P
S
S
V
R
T
A
G
L
K
P
E
T
G
P
Rat
Rattus norvegicus
Q6IE24
1588
176137
A1029
H
P
I
M
S
A
A
A
S
P
V
L
H
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512481
1110
122865
S866
I
K
D
E
L
P
S
S
P
A
K
A
T
G
S
Chicken
Gallus gallus
XP_420633
1049
117873
L852
Q
L
R
R
V
D
A
L
W
V
P
E
A
V
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570078
1746
191998
Q1242
L
K
E
L
Q
A
K
Q
A
N
D
L
R
A
M
Honey Bee
Apis mellifera
XP_394511
1962
219527
G1442
V
M
Q
T
Q
Q
S
G
L
N
Q
A
I
M
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.2
77
N.A.
75
28.5
N.A.
62.2
56.4
N.A.
N.A.
N.A.
23.3
23.7
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
82.9
N.A.
83
43.2
N.A.
72.9
67.9
N.A.
N.A.
N.A.
36.3
35.5
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
6.6
0
N.A.
0
0
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
20
6.6
N.A.
20
6.6
N.A.
N.A.
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
30
10
10
10
0
20
10
30
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
0
20
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
20
0
10
0
20
0
% G
% His:
10
0
0
0
30
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
20
0
0
0
0
10
0
0
10
10
30
0
10
0
% K
% Leu:
40
10
10
10
10
30
0
10
20
0
30
20
10
0
0
% L
% Met:
0
10
0
10
0
0
0
10
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% N
% Pro:
20
10
0
0
0
10
0
0
10
20
20
0
30
0
20
% P
% Gln:
10
0
10
0
20
10
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
10
10
0
30
0
10
10
0
0
10
0
0
% R
% Ser:
0
20
40
30
20
10
20
10
10
0
0
0
0
0
20
% S
% Thr:
0
0
0
10
0
10
0
30
0
0
0
0
20
0
30
% T
% Val:
10
0
0
10
10
0
0
0
30
10
20
0
0
10
0
% V
% Trp:
0
30
0
10
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _