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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP51
All Species:
9.09
Human Site:
S221
Identified Species:
15.38
UniProt:
Q70EK9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EK9
NP_958443.1
711
79756
S221
I
Y
Q
R
F
V
W
S
G
T
P
E
T
R
K
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S221
I
Y
Q
R
F
V
W
S
G
T
P
E
T
R
K
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
S221
I
Y
Q
R
F
V
W
S
G
T
P
E
T
R
K
Dog
Lupus familis
XP_548999
579
65084
K116
F
F
G
C
F
T
E
K
H
I
H
E
H
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
V62
K
R
K
A
K
S
C
V
C
H
V
C
G
I
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
L25
L
N
R
L
H
S
C
L
Y
C
V
F
F
G
C
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6GNI6
523
60030
C59
H
L
N
R
L
H
S
C
L
Y
C
V
F
F
G
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
K42
E
T
R
K
R
K
A
K
S
C
I
C
H
M
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
A238
A
S
A
D
A
S
S
A
V
M
S
E
T
G
C
Honey Bee
Apis mellifera
XP_395389
502
57164
I38
S
T
S
T
E
A
R
I
R
K
A
V
S
C
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
F121
E
R
L
N
C
S
K
F
H
G
I
V
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
A94
L
N
K
G
H
D
I
A
I
D
V
E
R
S
E
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.7
58.7
N.A.
54
N.A.
N.A.
49.3
20.1
52.3
51.2
N.A.
34.9
41.7
N.A.
43
Protein Similarity:
100
99.7
98.4
66.9
N.A.
60.9
N.A.
N.A.
56.2
30.6
60.4
59.2
N.A.
52.1
53
N.A.
53.1
P-Site Identity:
100
100
100
13.3
N.A.
0
N.A.
N.A.
0
0
6.6
0
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
6.6
N.A.
N.A.
13.3
0
6.6
13.3
N.A.
20
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45
34.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
8
15
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
8
8
0
15
8
8
15
8
15
0
8
22
% C
% Asp:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% D
% Glu:
15
0
0
0
8
0
8
0
0
0
0
43
0
0
15
% E
% Phe:
8
8
0
0
29
0
0
8
0
0
0
8
15
8
8
% F
% Gly:
0
0
8
8
0
0
0
0
22
8
0
0
8
22
8
% G
% His:
8
0
0
0
15
8
0
0
15
8
8
0
15
0
8
% H
% Ile:
22
0
0
0
0
0
8
8
8
8
15
0
0
8
0
% I
% Lys:
8
0
15
8
8
8
8
15
0
8
0
0
0
0
22
% K
% Leu:
15
8
8
8
8
0
0
8
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
15
8
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
22
0
0
0
0
% P
% Gln:
0
0
22
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
15
15
29
8
0
8
0
8
0
0
0
8
22
0
% R
% Ser:
8
8
8
0
0
29
15
22
8
0
8
0
8
8
0
% S
% Thr:
0
15
0
8
0
8
0
0
0
22
0
0
29
0
0
% T
% Val:
0
0
0
0
0
22
0
8
8
0
22
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _