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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP51 All Species: 9.09
Human Site: S316 Identified Species: 15.38
UniProt: Q70EK9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70EK9 NP_958443.1 711 79756 S316 L R L L T S T S T D V S H Q Q
Chimpanzee Pan troglodytes XP_521085 711 79749 S316 L R L L T S T S T D V S H Q Q
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 T316 L R L T S T S T D V S H Q Q F
Dog Lupus familis XP_548999 579 65084 T211 N P R R R R I T S S F T I G L
Cat Felis silvestris
Mouse Mus musculus Q5DU02 525 59935 L157 P T K R E L E L L K H N P K R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 L120 P T K R E L E L L R H N P K R
Chicken Gallus gallus O57429 357 40913
Frog Xenopus laevis Q6GNI6 523 60030 E154 E P T K R E L E L L Q H N P K
Zebra Danio Brachydanio rerio A6H8I0 506 58102 E137 M W E P T K R E L E L L R H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 C333 L S H G T L Y C Y A C R D F I
Honey Bee Apis mellifera XP_395389 502 57164 P133 E F Y R A W E P T Q I E A E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 Y216 T R V F Q E F Y S G I R S V H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 N189 L G S T C F M N A V L Q A L V
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 D101 L F C F K C E D Y I G N I D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.7 58.7 N.A. 54 N.A. N.A. 49.3 20.1 52.3 51.2 N.A. 34.9 41.7 N.A. 43
Protein Similarity: 100 99.7 98.4 66.9 N.A. 60.9 N.A. N.A. 56.2 30.6 60.4 59.2 N.A. 52.1 53 N.A. 53.1
P-Site Identity: 100 100 26.6 0 N.A. 0 N.A. N.A. 0 0 0 6.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 53.3 20 N.A. 20 N.A. N.A. 20 0 13.3 26.6 N.A. 13.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 28.1 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45 34.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 8 8 0 0 15 0 0 % A
% Cys: 0 0 8 0 8 8 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 8 15 0 0 8 8 0 % D
% Glu: 15 0 8 0 15 15 29 15 0 8 0 8 0 8 0 % E
% Phe: 0 15 0 15 0 8 8 0 0 0 8 0 0 8 8 % F
% Gly: 0 8 0 8 0 0 0 0 0 8 8 0 0 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 15 15 15 8 8 % H
% Ile: 0 0 0 0 0 0 8 0 0 8 15 0 15 0 8 % I
% Lys: 0 0 15 8 8 8 0 0 0 8 0 0 0 15 8 % K
% Leu: 43 0 22 15 0 22 8 15 29 8 15 8 0 8 22 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 22 8 0 8 % N
% Pro: 15 15 0 8 0 0 0 8 0 0 0 0 15 8 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 8 8 8 22 15 % Q
% Arg: 0 29 8 29 15 8 8 0 0 8 0 15 8 0 15 % R
% Ser: 0 8 8 0 8 15 8 15 15 8 8 15 8 0 0 % S
% Thr: 8 15 8 15 29 8 15 15 22 0 0 8 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 15 15 0 0 8 8 % V
% Trp: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 8 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _