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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP51 All Species: 16.36
Human Site: S420 Identified Species: 27.69
UniProt: Q70EK9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70EK9 NP_958443.1 711 79756 S420 S L F H A M Y S G S R T P H I
Chimpanzee Pan troglodytes XP_521085 711 79749 S420 S L F H A M Y S G S R T P H I
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 S419 S L F H A M Y S G S R T P H I
Dog Lupus familis XP_548999 579 65084 A312 D A H E F L I A A L D V L H R
Cat Felis silvestris
Mouse Mus musculus Q5DU02 525 59935 Y258 H A R H L A G Y E Q Q D A H E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 Y221 H A R H L A G Y E Q Q D A H E
Chicken Gallus gallus O57429 357 40913 S89 P N D S V S P S E F K T Q I Q
Frog Xenopus laevis Q6GNI6 523 60030 G255 T H A R H L A G Y E Q Q D A H
Zebra Danio Brachydanio rerio A6H8I0 506 58102 A238 W T H A R H L A G Y E Q Q D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 S454 R L F Q E F Y S G S R S P L S
Honey Bee Apis mellifera XP_395389 502 57164 R234 H L I W T H A R H L A G Y E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 S318 S L D L G P S S S S N S A P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 Y290 E G K S K C L Y Q D N E E C Q
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 Q202 Y G A L N T K Q A S S S S T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.7 58.7 N.A. 54 N.A. N.A. 49.3 20.1 52.3 51.2 N.A. 34.9 41.7 N.A. 43
Protein Similarity: 100 99.7 98.4 66.9 N.A. 60.9 N.A. N.A. 56.2 30.6 60.4 59.2 N.A. 52.1 53 N.A. 53.1
P-Site Identity: 100 100 100 6.6 N.A. 13.3 N.A. N.A. 13.3 13.3 0 6.6 N.A. 53.3 6.6 N.A. 26.6
P-Site Similarity: 100 100 100 20 N.A. 20 N.A. N.A. 20 20 20 13.3 N.A. 60 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 28.1 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45 34.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 15 8 22 15 15 15 15 0 8 0 22 8 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 15 0 0 0 0 0 0 8 8 15 8 8 0 % D
% Glu: 8 0 0 8 8 0 0 0 22 8 8 8 8 8 15 % E
% Phe: 0 0 29 0 8 8 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 15 0 0 8 0 15 8 36 0 0 8 0 0 0 % G
% His: 22 8 15 36 8 15 0 0 8 0 0 0 0 43 8 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 22 % I
% Lys: 0 0 8 0 8 0 8 0 0 0 8 0 0 0 0 % K
% Leu: 0 43 0 15 15 15 15 0 0 15 0 0 8 8 8 % L
% Met: 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 8 0 0 0 0 8 8 0 0 0 0 0 29 8 0 % P
% Gln: 0 0 0 8 0 0 0 8 8 15 22 15 15 0 22 % Q
% Arg: 8 0 15 8 8 0 0 8 0 0 29 0 0 0 8 % R
% Ser: 29 0 0 15 0 8 8 43 8 43 8 22 8 0 15 % S
% Thr: 8 8 0 0 8 8 0 0 0 0 0 29 0 8 0 % T
% Val: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 29 22 8 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _