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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP51 All Species: 9.39
Human Site: T223 Identified Species: 15.9
UniProt: Q70EK9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70EK9 NP_958443.1 711 79756 T223 Q R F V W S G T P E T R K R K
Chimpanzee Pan troglodytes XP_521085 711 79749 T223 Q R F V W S G T P E T R K R K
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 T223 Q R F V W S G T P E T R K R K
Dog Lupus familis XP_548999 579 65084 I118 G C F T E K H I H E H A E T K
Cat Felis silvestris
Mouse Mus musculus Q5DU02 525 59935 H64 K A K S C V C H V C G I H L N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 C27 R L H S C L Y C V F F G C F T
Chicken Gallus gallus O57429 357 40913
Frog Xenopus laevis Q6GNI6 523 60030 Y61 N R L H S C L Y C V F F G C F
Zebra Danio Brachydanio rerio A6H8I0 506 58102 C44 R K R K A K S C I C H M C G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 M240 A D A S S A V M S E T G C R H
Honey Bee Apis mellifera XP_395389 502 57164 K40 S T E A R I R K A V S C L C H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 G123 L N C S K F H G I V Q G F S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 D96 K G H D I A I D V E R S E L Y
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 Q8 M S I C P H I Q Q V F Q N E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.7 58.7 N.A. 54 N.A. N.A. 49.3 20.1 52.3 51.2 N.A. 34.9 41.7 N.A. 43
Protein Similarity: 100 99.7 98.4 66.9 N.A. 60.9 N.A. N.A. 56.2 30.6 60.4 59.2 N.A. 52.1 53 N.A. 53.1
P-Site Identity: 100 100 100 20 N.A. 0 N.A. N.A. 0 0 6.6 0 N.A. 20 0 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 6.6 N.A. N.A. 6.6 0 6.6 13.3 N.A. 26.6 6.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 28.1 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45 34.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 8 15 0 0 8 0 0 8 0 0 15 % A
% Cys: 0 8 8 8 15 8 8 15 8 15 0 8 22 15 0 % C
% Asp: 0 8 0 8 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 0 0 0 0 43 0 0 15 8 0 % E
% Phe: 0 0 29 0 0 8 0 0 0 8 22 8 8 8 8 % F
% Gly: 8 8 0 0 0 0 22 8 0 0 8 22 8 8 0 % G
% His: 0 0 15 8 0 8 15 8 8 0 15 0 8 0 15 % H
% Ile: 0 0 8 0 8 8 15 8 15 0 0 8 0 0 0 % I
% Lys: 15 8 8 8 8 15 0 8 0 0 0 0 22 0 36 % K
% Leu: 8 8 8 0 0 8 8 0 0 0 0 0 8 15 0 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 8 0 0 0 22 0 0 0 0 0 0 % P
% Gln: 22 0 0 0 0 0 0 8 8 0 8 8 0 0 0 % Q
% Arg: 15 29 8 0 8 0 8 0 0 0 8 22 0 29 0 % R
% Ser: 8 8 0 29 15 22 8 0 8 0 8 8 0 8 0 % S
% Thr: 0 8 0 8 0 0 0 22 0 0 29 0 0 8 8 % T
% Val: 0 0 0 22 0 8 8 0 22 29 0 0 0 0 0 % V
% Trp: 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _