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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP54
All Species:
7.27
Human Site:
S381
Identified Species:
16
UniProt:
Q70EL1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL1
NP_689799.3
1684
187388
S381
T
C
Y
D
S
E
D
S
G
R
E
P
S
I
S
Chimpanzee
Pan troglodytes
XP_517410
1073
120810
Rhesus Macaque
Macaca mulatta
XP_001098826
1073
120920
Dog
Lupus familis
XP_536391
1630
180793
P352
L
L
L
L
Y
A
D
P
Q
G
T
P
V
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BL06
1588
176645
K331
K
E
I
G
P
K
W
K
D
V
V
T
K
C
I
Rat
Rattus norvegicus
Q6IE24
1588
176137
K331
K
E
I
G
P
K
W
K
D
V
V
T
K
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520353
1641
182070
S381
T
C
Y
D
S
E
D
S
G
R
E
P
S
I
S
Chicken
Gallus gallus
XP_421621
1685
188505
S381
T
C
Y
D
S
E
D
S
G
H
L
T
D
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692367
1247
138353
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570078
1746
191998
V423
A
P
S
I
A
G
S
V
V
R
R
A
V
T
P
Honey Bee
Apis mellifera
XP_394511
1962
219527
N407
G
L
K
T
P
P
K
N
N
V
R
R
S
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.5
28
83.9
N.A.
75.3
74.6
N.A.
63.9
59.2
N.A.
42
N.A.
20.7
24.8
N.A.
N.A.
Protein Similarity:
100
40.7
41.3
87.4
N.A.
80.2
79
N.A.
72.7
69.3
N.A.
53
N.A.
37.5
40.2
N.A.
N.A.
P-Site Identity:
100
0
0
13.3
N.A.
0
0
N.A.
100
60
N.A.
0
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
0
0
20
N.A.
6.6
6.6
N.A.
100
60
N.A.
0
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
28
0
0
0
0
0
0
0
0
0
0
0
19
0
% C
% Asp:
0
0
0
28
0
0
37
0
19
0
0
0
10
0
0
% D
% Glu:
0
19
0
0
0
28
0
0
0
0
19
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
19
0
10
0
0
28
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
19
10
0
0
0
0
0
0
0
0
0
28
19
% I
% Lys:
19
0
10
0
0
19
10
19
0
0
0
0
19
0
0
% K
% Leu:
10
19
10
10
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
28
10
0
10
0
0
0
28
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
28
19
10
0
0
0
% R
% Ser:
0
0
10
0
28
0
10
28
0
0
0
0
28
19
19
% S
% Thr:
28
0
0
10
0
0
0
0
0
0
10
28
0
10
19
% T
% Val:
0
0
0
0
0
0
0
10
10
28
19
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
28
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _