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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP54 All Species: 6.97
Human Site: S388 Identified Species: 15.33
UniProt: Q70EL1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70EL1 NP_689799.3 1684 187388 S388 S G R E P S I S S D T R T D S
Chimpanzee Pan troglodytes XP_517410 1073 120810
Rhesus Macaque Macaca mulatta XP_001098826 1073 120920
Dog Lupus familis XP_536391 1630 180793 T359 P Q G T P V S T Q D L P P Q V
Cat Felis silvestris
Mouse Mus musculus Q8BL06 1588 176645 I338 K D V V T K C I K G H Y Q P L
Rat Rattus norvegicus Q6IE24 1588 176137 I338 K D V V T K C I K G H Y Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520353 1641 182070 S388 S G R E P S I S S D T R T D S
Chicken Gallus gallus XP_421621 1685 188505 E388 S G H L T D S E C N Q R H I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692367 1247 138353
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_570078 1746 191998 P430 V V R R A V T P S P E K P S L
Honey Bee Apis mellifera XP_394511 1962 219527 T414 N N V R R S I T P S P E K P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.5 28 83.9 N.A. 75.3 74.6 N.A. 63.9 59.2 N.A. 42 N.A. 20.7 24.8 N.A. N.A.
Protein Similarity: 100 40.7 41.3 87.4 N.A. 80.2 79 N.A. 72.7 69.3 N.A. 53 N.A. 37.5 40.2 N.A. N.A.
P-Site Identity: 100 0 0 13.3 N.A. 0 0 N.A. 100 26.6 N.A. 0 N.A. 13.3 20 N.A. N.A.
P-Site Similarity: 100 0 0 20 N.A. 0 0 N.A. 100 33.3 N.A. 0 N.A. 20 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 10 0 0 0 28 0 0 0 19 0 % D
% Glu: 0 0 0 19 0 0 0 10 0 0 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 28 10 0 0 0 0 0 0 19 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 19 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 28 19 0 0 0 0 0 10 0 % I
% Lys: 19 0 0 0 0 19 0 0 19 0 0 10 10 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 28 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 0 28 0 0 10 10 10 10 10 19 28 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 10 0 19 10 0 % Q
% Arg: 0 0 28 19 10 0 0 0 0 0 0 28 0 0 0 % R
% Ser: 28 0 0 0 0 28 19 19 28 10 0 0 0 10 37 % S
% Thr: 0 0 0 10 28 0 10 19 0 0 19 0 19 0 0 % T
% Val: 10 10 28 19 0 19 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _