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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
16.06
Human Site:
S433
Identified Species:
27.18
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S433
A
A
K
K
H
S
S
S
K
D
K
S
Q
L
I
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S433
A
A
K
K
H
S
S
S
K
D
K
S
Q
L
I
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S434
A
A
K
K
H
S
S
S
K
D
K
S
Q
L
I
Dog
Lupus familis
XP_539054
796
87704
R425
I
E
T
T
H
Q
P
R
A
T
Q
S
S
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
S432
P
R
A
S
R
K
H
S
S
P
N
D
K
N
Q
Rat
Rattus norvegicus
Q2KJ09
826
93743
T437
P
S
G
T
S
K
H
T
Q
K
K
A
K
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
Q427
V
T
A
V
N
H
Q
Q
P
K
D
P
R
K
N
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6PAW2
901
101274
Q438
P
G
A
S
K
H
L
Q
K
K
A
K
K
A
A
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
T444
N
E
D
M
P
T
G
T
G
S
K
Y
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
S447
A
A
R
K
N
R
K
S
K
K
Q
E
I
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
K461
A
S
A
T
E
E
T
K
P
L
S
K
H
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
D538
K
D
H
L
F
Y
D
D
Y
M
V
A
E
A
S
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
Y102
F
C
F
K
C
E
D
Y
I
G
N
I
D
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
0
0
6.6
13.3
N.A.
N.A.
33.3
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
13.3
40
N.A.
13.3
0
13.3
26.6
N.A.
N.A.
53.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
29
29
0
0
0
0
0
8
0
8
15
0
15
8
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
15
8
0
22
8
8
8
0
0
% D
% Glu:
0
15
0
0
8
15
0
0
0
0
0
8
8
0
0
% E
% Phe:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
8
0
8
8
0
0
0
0
0
% G
% His:
0
0
8
0
29
15
15
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
8
8
0
36
% I
% Lys:
8
0
22
36
8
15
8
8
36
29
36
15
22
15
15
% K
% Leu:
0
0
0
8
0
0
8
0
0
8
0
0
0
29
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
15
0
0
0
0
0
15
0
0
8
8
% N
% Pro:
22
0
0
0
8
0
8
0
15
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
15
8
0
15
0
29
15
22
% Q
% Arg:
0
8
8
0
8
8
0
8
0
0
0
0
8
8
0
% R
% Ser:
0
15
0
15
8
22
22
36
8
8
8
29
8
8
8
% S
% Thr:
0
8
8
22
0
8
8
15
0
8
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _