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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
12.42
Human Site:
S480
Identified Species:
21.03
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S480
A
S
L
M
N
S
E
S
R
L
N
E
S
P
T
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S480
A
S
L
M
N
S
E
S
R
L
N
E
S
P
T
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S481
A
R
L
M
N
S
E
S
P
L
N
E
S
P
T
Dog
Lupus familis
XP_539054
796
87704
A472
H
S
F
P
P
E
G
A
E
S
P
E
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
E479
P
A
S
T
L
S
T
E
A
S
L
N
E
S
L
Rat
Rattus norvegicus
Q2KJ09
826
93743
A484
N
D
H
E
A
E
T
A
L
P
G
E
G
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
N474
R
R
E
T
V
G
M
N
G
G
S
G
G
P
S
Chicken
Gallus gallus
O57429
357
40913
L34
T
C
F
M
N
S
I
L
Q
C
L
S
N
T
K
Frog
Xenopus laevis
Q6PAW2
901
101274
T485
E
E
V
S
Q
T
K
T
N
T
R
P
D
N
E
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
S491
S
T
D
P
A
D
S
S
M
Q
T
Q
T
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
G494
E
G
L
L
P
E
V
G
E
S
G
Y
S
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
N508
D
S
P
I
Q
S
D
N
E
E
E
E
R
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
V585
R
P
L
S
K
S
E
V
Y
E
A
G
F
K
A
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
S149
M
G
S
T
C
F
M
S
S
I
L
Q
C
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
86.6
13.3
N.A.
6.6
6.6
N.A.
6.6
20
0
6.6
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
86.6
26.6
N.A.
13.3
13.3
N.A.
26.6
33.3
26.6
40
N.A.
N.A.
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
0
0
15
0
0
15
8
0
8
0
8
0
8
% A
% Cys:
0
8
0
0
8
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
8
8
8
0
0
8
8
0
0
0
0
0
8
0
0
% D
% Glu:
15
8
8
8
0
22
29
8
22
15
8
43
8
8
22
% E
% Phe:
0
0
15
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
15
0
0
0
8
8
8
8
8
15
15
15
0
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
36
8
8
0
0
8
8
22
22
0
0
8
8
% L
% Met:
8
0
0
29
0
0
15
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
29
0
0
15
8
0
22
8
8
8
0
% N
% Pro:
8
8
8
15
15
0
0
0
8
8
8
8
0
29
0
% P
% Gln:
0
0
0
0
15
0
0
0
8
8
0
15
0
0
0
% Q
% Arg:
15
15
0
0
0
0
0
0
15
0
8
0
8
8
0
% R
% Ser:
8
29
15
15
0
50
8
36
8
22
8
8
29
22
15
% S
% Thr:
8
8
0
22
0
8
15
8
0
8
8
0
8
8
22
% T
% Val:
0
0
8
0
8
0
8
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _