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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
14.55
Human Site:
S490
Identified Species:
24.62
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S490
N
E
S
P
T
D
D
S
E
K
E
A
S
H
S
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S490
N
E
S
P
T
D
D
S
E
K
E
A
S
H
S
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S491
N
E
S
P
T
D
D
S
E
K
E
A
S
H
S
Dog
Lupus familis
XP_539054
796
87704
A482
P
E
A
S
G
G
E
A
G
G
E
A
G
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
G489
L
N
E
S
L
T
D
G
S
E
R
D
A
S
L
Rat
Rattus norvegicus
Q2KJ09
826
93743
E494
G
E
G
E
V
D
T
E
F
N
R
G
S
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
T484
S
G
G
P
S
I
L
T
P
Q
D
V
H
R
A
Chicken
Gallus gallus
O57429
357
40913
R44
L
S
N
T
K
E
L
R
D
Y
C
L
Q
N
Q
Frog
Xenopus laevis
Q6PAW2
901
101274
T495
R
P
D
N
E
T
P
T
A
D
G
L
N
T
M
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
G501
T
Q
T
V
S
V
N
G
S
A
D
A
Q
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
S504
G
Y
S
S
E
K
Q
S
T
L
A
S
P
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
V518
E
E
R
R
E
E
G
V
G
Y
R
D
P
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
S595
A
G
F
K
A
D
C
S
D
D
K
T
V
S
A
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
P159
L
Q
C
L
I
H
N
P
Y
F
I
R
H
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
100
26.6
N.A.
6.6
20
N.A.
6.6
0
0
6.6
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
100
46.6
N.A.
20
20
N.A.
46.6
26.6
13.3
46.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
8
8
8
8
36
8
15
22
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
36
29
0
15
15
15
15
0
0
8
% D
% Glu:
8
43
8
8
22
15
8
8
22
8
29
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
15
15
15
0
8
8
8
15
15
8
8
8
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
15
22
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
8
8
0
0
0
22
8
0
0
0
0
% K
% Leu:
22
0
0
8
8
0
15
0
0
8
0
15
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
22
8
8
8
0
0
15
0
0
8
0
0
8
15
0
% N
% Pro:
8
8
0
29
0
0
8
8
8
0
0
0
15
8
0
% P
% Gln:
0
15
0
0
0
0
8
0
0
8
0
0
15
8
8
% Q
% Arg:
8
0
8
8
0
0
0
8
0
0
22
8
0
8
0
% R
% Ser:
8
8
29
22
15
0
0
36
15
0
0
8
29
22
36
% S
% Thr:
8
0
8
8
22
15
8
15
8
0
0
8
0
8
0
% T
% Val:
0
0
0
8
8
8
0
8
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _