KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
12.42
Human Site:
S565
Identified Species:
21.03
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S565
A
I
S
E
L
R
L
S
S
T
V
T
G
D
Q
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S565
A
I
S
E
L
R
L
S
S
T
V
T
G
D
Q
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
R566
A
I
S
E
L
H
L
R
S
T
V
T
G
H
Q
Dog
Lupus familis
XP_539054
796
87704
A557
T
V
T
G
P
R
A
A
Q
R
D
D
Q
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
S564
A
I
A
E
L
H
L
S
G
T
V
T
G
N
R
Rat
Rattus norvegicus
Q2KJ09
826
93743
S569
A
F
L
E
E
R
T
S
G
E
L
D
I
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
F559
S
Q
L
S
L
G
G
F
G
P
G
G
R
P
R
Chicken
Gallus gallus
O57429
357
40913
D119
E
F
L
R
F
L
L
D
G
L
H
G
E
V
N
Frog
Xenopus laevis
Q6PAW2
901
101274
D570
E
G
I
T
E
H
T
D
L
D
S
S
V
H
N
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
E576
A
E
E
E
E
L
V
E
E
L
N
T
M
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
S579
G
L
D
T
L
D
S
S
E
S
F
E
N
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
L593
G
S
T
D
R
L
S
L
S
S
R
A
S
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
A670
V
S
A
G
K
G
E
A
S
S
S
F
V
S
S
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
S234
N
Q
N
L
A
G
Y
S
Q
Q
D
A
H
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
80
6.6
N.A.
66.6
26.6
N.A.
6.6
6.6
0
20
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
80
26.6
N.A.
86.6
33.3
N.A.
20
6.6
6.6
26.6
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
15
0
8
0
8
15
0
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
15
0
8
15
15
0
15
0
% D
% Glu:
15
8
8
43
22
0
8
8
15
8
0
8
8
15
0
% E
% Phe:
0
15
0
0
8
0
0
8
0
0
8
8
0
0
8
% F
% Gly:
15
8
0
15
0
22
8
0
29
0
8
15
29
0
0
% G
% His:
0
0
0
0
0
22
0
0
0
0
8
0
8
15
0
% H
% Ile:
0
29
8
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
22
8
43
22
36
8
8
15
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
8
0
8
8
22
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
0
0
15
8
% P
% Gln:
0
15
0
0
0
0
0
0
15
8
0
0
8
0
22
% Q
% Arg:
0
0
0
8
8
29
0
8
0
8
8
0
8
0
15
% R
% Ser:
8
15
22
8
0
0
15
43
36
22
15
8
8
15
22
% S
% Thr:
8
0
15
15
0
0
15
0
0
29
0
36
0
15
0
% T
% Val:
8
8
0
0
0
0
8
0
0
0
29
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _