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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
12.73
Human Site:
T417
Identified Species:
21.54
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
T417
D
R
Y
S
G
N
V
T
I
E
N
I
H
Q
P
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
T417
D
R
Y
S
G
N
V
T
I
E
N
I
H
Q
P
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
T418
D
R
Y
N
G
N
V
T
V
E
N
I
H
Q
P
Dog
Lupus familis
XP_539054
796
87704
D409
R
S
L
Q
V
T
D
D
G
Q
Y
G
D
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
T416
D
Q
D
H
N
K
G
T
V
T
V
G
N
A
H
Rat
Rattus norvegicus
Q2KJ09
826
93743
S421
S
E
E
E
K
D
D
S
Y
M
K
T
R
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
E411
C
K
T
L
Q
E
A
E
L
G
Q
Y
S
C
S
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6PAW2
901
101274
Y422
E
E
N
D
D
D
R
Y
V
K
E
R
D
E
V
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
Q428
S
V
S
D
D
G
D
Q
D
T
S
S
L
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
K431
N
I
S
H
V
P
S
K
H
Q
L
K
K
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
Q445
S
S
N
D
G
D
K
Q
T
L
A
A
T
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
D522
E
L
A
L
M
V
A
D
S
Q
V
L
Y
M
P
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
G86
K
Q
I
G
H
I
F
G
I
N
S
N
N
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
86.6
0
N.A.
13.3
0
N.A.
0
0
0
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
33.3
13.3
N.A.
13.3
0
33.3
6.6
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
15
0
0
0
8
8
0
22
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
29
0
8
22
15
22
22
15
8
0
0
0
15
0
8
% D
% Glu:
15
15
8
8
0
8
0
8
0
22
8
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
29
8
8
8
8
8
0
15
0
8
0
% G
% His:
0
0
0
15
8
0
0
0
8
0
0
0
22
0
8
% H
% Ile:
0
8
8
0
0
8
0
0
22
0
0
22
0
0
0
% I
% Lys:
8
8
0
0
8
8
8
8
0
8
8
8
8
0
8
% K
% Leu:
0
8
8
15
0
0
0
0
8
8
8
8
8
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
8
0
15
8
8
22
0
0
0
8
22
8
15
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
29
% P
% Gln:
0
15
0
8
8
0
0
15
0
22
8
0
0
22
0
% Q
% Arg:
8
22
0
0
0
0
8
0
0
0
0
8
8
0
0
% R
% Ser:
22
15
15
15
0
0
8
8
8
0
15
8
8
8
8
% S
% Thr:
0
0
8
0
0
8
0
29
8
15
0
8
8
8
0
% T
% Val:
0
8
0
0
15
8
22
0
22
0
15
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
0
0
8
8
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _