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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
24.85
Human Site:
T748
Identified Species:
42.05
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
T748
S
M
R
E
G
H
Y
T
A
Y
V
K
V
R
T
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
T748
S
M
R
E
G
H
Y
T
A
Y
V
K
V
R
T
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
T749
S
M
R
E
G
H
Y
T
A
Y
V
K
V
R
T
Dog
Lupus familis
XP_539054
796
87704
T730
S
M
R
G
G
H
Y
T
A
Y
V
K
V
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
T747
S
M
R
G
G
H
Y
T
A
Y
V
K
V
R
V
Rat
Rattus norvegicus
Q2KJ09
826
93743
H760
S
G
T
M
R
S
G
H
Y
T
A
Y
A
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
T733
S
M
R
G
G
H
Y
T
A
Y
V
K
V
R
G
Chicken
Gallus gallus
O57429
357
40913
A291
A
S
Q
S
C
N
H
A
V
Y
N
L
Y
A
V
Frog
Xenopus laevis
Q6PAW2
901
101274
H835
S
G
S
M
R
S
G
H
Y
T
A
F
V
K
L
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
R749
V
E
H
S
G
T
M
R
S
G
H
Y
T
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
K778
R
W
S
F
L
P
S
K
D
I
K
N
T
Q
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
T980
R
L
Q
F
G
H
Y
T
A
F
V
K
V
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
E936
P
A
S
D
N
E
C
E
N
W
E
D
L
A
V
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
V406
K
H
S
E
N
G
K
V
P
D
I
I
Y
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
86.6
6.6
13.3
6.6
N.A.
N.A.
0
N.A.
60
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
86.6
33.3
20
13.3
N.A.
N.A.
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
50
0
15
0
8
22
0
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
0
% D
% Glu:
0
8
0
29
0
8
0
8
0
0
8
0
0
8
15
% E
% Phe:
0
0
0
15
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
15
0
22
58
8
15
0
0
8
0
0
0
0
8
% G
% His:
0
8
8
0
0
50
8
15
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
8
0
0
8
50
0
15
0
% K
% Leu:
0
8
0
0
8
0
0
0
0
0
0
8
8
0
15
% L
% Met:
0
43
0
15
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
8
0
0
8
0
8
8
0
0
0
% N
% Pro:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
15
0
43
0
15
0
0
8
0
0
0
0
0
50
0
% R
% Ser:
58
8
29
15
0
15
8
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
50
0
15
0
0
15
0
29
% T
% Val:
8
0
0
0
0
0
0
8
8
0
50
0
58
0
22
% V
% Trp:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
0
15
50
0
15
15
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _