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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
15.15
Human Site:
T765
Identified Species:
25.64
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
T765
R
K
L
S
E
H
N
T
K
K
K
N
V
P
G
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
T765
R
K
L
S
E
H
N
T
K
K
K
N
V
P
G
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
T766
R
K
L
S
E
H
P
T
K
K
K
S
V
P
G
Dog
Lupus familis
XP_539054
796
87704
T747
R
K
L
L
E
H
I
T
G
E
K
N
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
T764
R
K
L
S
E
C
I
T
G
R
K
T
A
A
G
Rat
Rattus norvegicus
Q2KJ09
826
93743
L777
A
S
C
H
L
S
N
L
V
L
H
G
D
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
A750
K
A
S
L
E
H
V
A
G
I
Q
N
V
Q
G
Chicken
Gallus gallus
O57429
357
40913
G308
H
S
G
T
T
M
G
G
H
Y
T
A
Y
C
K
Frog
Xenopus laevis
Q6PAW2
901
101274
M852
P
N
Q
Q
L
C
K
M
L
F
T
G
V
I
P
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
C766
S
R
P
S
T
H
N
C
V
Q
N
G
T
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
E795
Y
S
S
S
S
E
S
E
T
E
E
A
A
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
L997
E
T
L
T
L
Y
T
L
G
I
P
R
T
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
D953
E
E
V
I
V
K
R
D
A
R
K
K
V
L
I
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
V423
I
V
S
H
K
G
T
V
N
E
G
H
Y
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
86.6
73.3
N.A.
53.3
6.6
N.A.
33.3
0
6.6
20
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
60
6.6
N.A.
46.6
6.6
6.6
33.3
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
8
0
0
15
15
22
15
% A
% Cys:
0
0
8
0
0
15
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
15
8
0
0
43
8
0
8
0
22
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
8
8
29
0
8
22
0
0
43
% G
% His:
8
0
0
15
0
43
0
0
8
0
8
8
0
0
0
% H
% Ile:
8
0
0
8
0
0
15
0
0
15
0
0
0
22
8
% I
% Lys:
8
36
0
0
8
8
8
0
22
22
43
8
0
0
8
% K
% Leu:
0
0
43
15
22
0
0
15
8
8
0
0
0
15
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
29
0
8
0
8
29
0
0
8
% N
% Pro:
8
0
8
0
0
0
8
0
0
0
8
0
0
29
15
% P
% Gln:
0
0
8
8
0
0
0
0
0
8
8
0
0
8
0
% Q
% Arg:
36
8
0
0
0
0
8
0
0
15
0
8
0
0
0
% R
% Ser:
8
22
22
43
8
8
8
0
0
0
0
8
0
0
8
% S
% Thr:
0
8
0
15
15
0
15
36
8
0
15
8
15
0
0
% T
% Val:
0
8
8
0
8
0
8
8
15
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
8
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _