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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP43
All Species:
16.67
Human Site:
Y134
Identified Species:
40.74
UniProt:
Q70EL4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL4
NP_694942.3
1124
122956
Y134
E
F
L
A
L
G
R
Y
R
A
A
P
G
R
A
Chimpanzee
Pan troglodytes
XP_511843
1810
198756
Y821
E
F
L
A
L
G
R
Y
Q
A
A
P
G
R
A
Rhesus Macaque
Macaca mulatta
XP_001118238
1783
194926
G803
G
D
G
A
R
P
P
G
A
Q
G
L
K
N
H
Dog
Lupus familis
XP_546616
1104
120856
Y107
E
F
L
A
L
G
R
Y
R
A
A
P
G
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUM9
1132
123856
Y134
E
F
L
A
L
G
R
Y
R
A
A
P
G
R
A
Rat
Rattus norvegicus
NP_001119775
1039
114738
L88
L
E
F
L
L
W
L
L
D
R
V
H
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509900
1226
134550
K85
E
A
D
S
I
V
S
K
N
A
L
Q
Y
R
G
Chicken
Gallus gallus
XP_426827
305
34386
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082871
1122
124879
Y147
E
Y
L
G
L
E
Q
Y
K
Y
E
L
N
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611959
1272
138793
S310
K
R
R
N
K
I
N
S
R
K
F
G
T
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.8
51.8
73.8
N.A.
80.4
72.4
N.A.
35.9
20.5
N.A.
49.6
N.A.
29.3
N.A.
N.A.
N.A.
Protein Similarity:
100
61.9
56
79.6
N.A.
86.3
78.3
N.A.
51.8
23.5
N.A.
63.2
N.A.
44.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
100
N.A.
100
6.6
N.A.
20
0
N.A.
26.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
33.3
0
N.A.
46.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
50
0
0
0
0
10
50
40
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
60
10
0
0
0
10
0
0
0
0
10
0
10
10
0
% E
% Phe:
0
40
10
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
10
10
0
40
0
10
0
0
10
10
40
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
10
10
10
0
0
10
10
0
% K
% Leu:
10
0
50
10
60
0
10
10
0
0
10
20
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
0
40
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
10
0
10
0
0
0
% Q
% Arg:
0
10
10
0
10
0
40
0
40
10
0
0
0
50
10
% R
% Ser:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
50
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _