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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A26 All Species: 15.45
Human Site: S121 Identified Species: 28.33
UniProt: Q70HW3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70HW3 NP_775742.3 274 29381 S121 Q R A Q V S A S T R T F Q I F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090674 274 29369 S121 Q R A Q V S A S T R T F Q I F
Dog Lupus familis XP_853770 274 29353 S121 Q R A Q V S A S S R T F Q I F
Cat Felis silvestris
Mouse Mus musculus Q5U680 274 29008 S121 Q R A Q V S A S S K T L Q I F
Rat Rattus norvegicus Q505J6 320 34152 R168 G S T S T H R R P S A T L I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510993 209 23002 L60 I P A L D C P L T V L G P S L
Chicken Gallus gallus
Frog Xenopus laevis Q641C8 266 28664 V117 V I K Q R A Q V S P S S T T Y
Zebra Danio Brachydanio rerio Q4V9P0 267 28976 Q114 V P T E V V K Q R T Q A N P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VBN7 283 31020 Q131 Q T L Q G N K Q S G L Q I L L
Honey Bee Apis mellifera XP_393015 274 30516 V123 I R V P V E V V K Q R R Q A L
Nematode Worm Caenorhab. elegans Q23125 312 34075 S147 Q R M Q M A F S P Y G S S L E
Sea Urchin Strong. purpuratus XP_796953 271 29475 R122 K Q R A Q A T R Q A S S G I F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38921 284 31008 K119 R V P A E V V K Q R T Q V H S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.6 91.6 N.A. 87.9 29.3 N.A. 42.3 N.A. 73.7 67.8 N.A. 49.1 41.9 24.3 54.7
Protein Similarity: 100 N.A. 97.4 95.6 N.A. 92.6 43.1 N.A. 51.4 N.A. 82.1 77 N.A. 62.9 58.3 43.9 68.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 80 6.6 N.A. 13.3 N.A. 6.6 6.6 N.A. 13.3 20 26.6 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 6.6 N.A. 13.3 N.A. 33.3 13.3 N.A. 33.3 26.6 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 45.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 64.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 39 16 0 24 31 0 0 8 8 8 0 8 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 24 0 0 39 % F
% Gly: 8 0 0 0 8 0 0 0 0 8 8 8 8 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 16 8 0 0 0 0 0 0 0 0 0 0 8 47 0 % I
% Lys: 8 0 8 0 0 0 16 8 8 8 0 0 0 0 0 % K
% Leu: 0 0 8 8 0 0 0 8 0 0 16 8 8 16 24 % L
% Met: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 16 8 8 0 0 8 0 16 8 0 0 8 8 0 % P
% Gln: 47 8 0 54 8 0 8 16 16 8 8 16 39 0 0 % Q
% Arg: 8 47 8 0 8 0 8 16 8 31 8 8 0 0 0 % R
% Ser: 0 8 0 8 0 31 0 39 31 8 16 24 8 8 16 % S
% Thr: 0 8 16 0 8 0 8 0 24 8 39 8 8 8 0 % T
% Val: 16 8 8 0 47 16 16 16 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _