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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC13D
All Species:
19.09
Human Site:
S150
Identified Species:
46.67
UniProt:
Q70J99
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70J99
NP_954712.1
1090
123282
S150
G
V
G
V
P
G
G
S
P
G
S
R
H
R
Q
Chimpanzee
Pan troglodytes
XP_001147065
1090
123277
S150
G
V
G
V
P
G
G
S
P
G
S
R
Q
R
Q
Rhesus Macaque
Macaca mulatta
XP_001100477
1090
123111
S150
G
V
S
V
P
G
G
S
P
G
S
R
H
R
Q
Dog
Lupus familis
XP_540438
1091
123215
S150
G
V
G
V
P
G
D
S
P
G
S
R
H
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
B2RUP2
1085
123101
S149
K
V
G
V
A
E
G
S
P
V
S
R
R
R
Q
Rat
Rattus norvegicus
Q9R189
1088
123436
S150
K
V
G
V
P
E
G
S
P
V
S
R
R
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415627
1067
122325
H129
S
K
N
Q
E
P
A
H
P
D
S
K
R
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692524
1104
126876
G170
E
D
K
E
S
P
G
G
G
A
S
N
K
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648096
1371
154112
R427
F
R
L
S
F
K
R
R
E
A
G
R
R
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001024711
1265
144994
P276
G
T
R
K
E
N
Q
P
M
T
D
S
A
H
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.8
89.7
N.A.
87.8
87.1
N.A.
N.A.
63.5
N.A.
44.1
N.A.
27
N.A.
25.6
N.A.
Protein Similarity:
100
99.3
98.2
94.5
N.A.
92.6
91.9
N.A.
N.A.
78.4
N.A.
63.5
N.A.
42.8
N.A.
42.5
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
66.6
73.3
N.A.
N.A.
20
N.A.
20
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
66.6
73.3
N.A.
N.A.
26.6
N.A.
20
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
20
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
10
10
0
0
0
0
% D
% Glu:
10
0
0
10
20
20
0
0
10
0
0
0
0
10
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
50
0
0
40
60
10
10
40
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
30
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
10
10
10
0
10
0
0
0
0
0
10
10
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
50
20
0
10
70
0
0
0
0
10
10
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
80
% Q
% Arg:
0
10
10
0
0
0
10
10
0
0
0
70
40
70
0
% R
% Ser:
10
0
10
10
10
0
0
60
0
0
80
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
60
0
60
0
0
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _