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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHSY3 All Species: 27.58
Human Site: Y545 Identified Species: 60.67
UniProt: Q70JA7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70JA7 NP_787052.3 882 100284 Y545 I L D L L L L Y K R H K G R K
Chimpanzee Pan troglodytes XP_001160577 882 100238 Y545 I L D L L L L Y K R H K G R K
Rhesus Macaque Macaca mulatta XP_001099447 882 99929 Y545 I L D L L L L Y K R H K G R K
Dog Lupus familis XP_538613 884 100305 Y547 I L D L L L L Y K R H K G R K
Cat Felis silvestris
Mouse Mus musculus Q5DTK1 884 100036 Y547 I L D L L L L Y K R H K G R K
Rat Rattus norvegicus XP_225912 886 100169 Y547 I L D L L L L Y K R H K G R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413966 812 91622 Y502 I L D L L L L Y K R H K G R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997843 801 91813 A488 L E E E E M D A R V L A A R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996440 832 95745 A507 S L F Q N G M A R L S S H F T
Honey Bee Apis mellifera XP_396991 814 93848 R490 R K V T L P V R R H V Y L H Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784554 785 89701 S489 G G F Q S S L S I F G H K T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.1 94.8 N.A. 91.5 90.4 N.A. N.A. 76.5 N.A. 59.6 N.A. 38.2 39.4 N.A. 40.8
Protein Similarity: 100 99.8 97.3 97.5 N.A. 94.9 94.2 N.A. N.A. 83.3 N.A. 71.8 N.A. 56.7 56.6 N.A. 56.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 33.3 N.A. 20 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 0 0 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 64 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 10 10 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 19 0 0 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 10 10 0 0 0 10 0 0 0 0 10 0 64 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 64 10 10 10 0 % H
% Ile: 64 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 64 0 0 64 10 0 64 % K
% Leu: 10 73 0 64 73 64 73 0 0 10 10 0 10 0 0 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 0 0 0 0 0 0 10 28 64 0 0 0 73 0 % R
% Ser: 10 0 0 0 10 10 0 10 0 0 10 10 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 10 0 0 0 10 0 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _