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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHSY3
All Species:
20.91
Human Site:
Y677
Identified Species:
46
UniProt:
Q70JA7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70JA7
NP_787052.3
882
100284
Y677
H
I
E
L
I
K
G
Y
Q
N
K
Y
P
K
A
Chimpanzee
Pan troglodytes
XP_001160577
882
100238
Y677
H
I
E
L
I
K
G
Y
Q
N
K
Y
P
K
A
Rhesus Macaque
Macaca mulatta
XP_001099447
882
99929
Y677
H
I
E
L
I
K
G
Y
Q
N
K
Y
P
K
A
Dog
Lupus familis
XP_538613
884
100305
Y679
H
I
E
L
I
K
E
Y
Q
N
R
Y
P
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5DTK1
884
100036
Y679
H
I
E
L
I
Q
E
Y
Q
S
R
Y
P
S
A
Rat
Rattus norvegicus
XP_225912
886
100169
Y681
H
I
E
L
I
Q
E
Y
Q
N
R
Y
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413966
812
91622
A613
P
R
Q
N
V
K
L
A
I
I
L
F
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997843
801
91813
D596
R
M
K
Y
P
K
A
D
M
E
I
K
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996440
832
95745
V625
D
I
I
L
F
I
D
V
D
M
V
F
E
V
E
Honey Bee
Apis mellifera
XP_396991
814
93848
L602
T
I
D
L
V
E
R
L
K
Y
K
Y
R
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784554
785
89701
A598
G
L
A
L
E
L
G
A
G
Q
Y
G
P
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.1
94.8
N.A.
91.5
90.4
N.A.
N.A.
76.5
N.A.
59.6
N.A.
38.2
39.4
N.A.
40.8
Protein Similarity:
100
99.8
97.3
97.5
N.A.
94.9
94.2
N.A.
N.A.
83.3
N.A.
71.8
N.A.
56.7
56.6
N.A.
56.6
P-Site Identity:
100
100
100
80
N.A.
66.6
73.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
13.3
33.3
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
26.6
N.A.
33.3
N.A.
20
60
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
19
0
0
0
0
0
0
73
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
10
10
10
0
0
0
0
10
0
% D
% Glu:
0
0
55
0
10
10
28
0
0
10
0
0
10
0
19
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
10
0
0
0
0
0
37
0
10
0
0
10
0
0
0
% G
% His:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
10
0
55
10
0
0
10
10
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
55
0
0
10
0
37
10
0
28
0
% K
% Leu:
0
10
0
82
0
10
10
10
0
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
46
0
0
0
10
0
% N
% Pro:
10
0
0
0
10
0
0
0
0
0
0
0
73
0
0
% P
% Gln:
0
0
10
0
0
19
0
0
55
10
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
10
0
0
0
28
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
10
37
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
19
0
0
10
0
0
10
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
55
0
10
10
64
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _