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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREX2
All Species:
21.52
Human Site:
Y745
Identified Species:
59.17
UniProt:
Q70Z35
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70Z35
NP_079146.2
1606
182622
Y745
H
V
T
A
C
R
K
Y
R
R
P
T
K
Q
D
Chimpanzee
Pan troglodytes
XP_519798
1764
199053
Y903
H
V
T
A
C
R
K
Y
R
R
P
M
K
Q
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544113
1591
181005
Y745
H
V
T
A
C
R
K
Y
R
R
P
M
K
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3LAC4
1598
181698
Y737
H
V
T
A
C
R
K
Y
K
R
P
M
K
Q
D
Rat
Rattus norvegicus
NP_001101369
1216
137976
E404
V
F
L
R
P
F
P
E
V
D
C
F
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511286
1603
182076
F745
H
V
T
A
C
R
K
F
R
R
P
M
Q
Q
D
Chicken
Gallus gallus
XP_418285
1710
193359
Y849
H
V
T
A
C
R
K
Y
R
R
P
M
Q
Q
D
Frog
Xenopus laevis
NP_001083702
1639
186749
N750
H
F
T
A
F
R
N
N
P
Q
N
S
L
G
L
Zebra Danio
Brachydanio rerio
XP_001923357
1600
182141
Y744
H
V
T
A
C
R
K
Y
R
R
P
T
Q
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97
N.A.
93.2
71.6
N.A.
93.9
85.4
57.1
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.9
N.A.
98.5
N.A.
96.9
74.2
N.A.
97.5
90.6
74.8
90.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
86.6
0
N.A.
80
86.6
26.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
6.6
N.A.
93.3
93.3
40
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
78
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
78
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
23
0
0
12
12
0
12
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
78
0
12
0
0
0
45
12
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
0
23
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
12
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
12
0
12
0
78
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
34
78
0
% Q
% Arg:
0
0
0
12
0
89
0
0
67
78
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% S
% Thr:
0
0
89
0
0
0
0
0
0
0
0
23
0
0
0
% T
% Val:
12
78
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _