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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRA10AC1 All Species: 16.97
Human Site: S244 Identified Species: 24.89
UniProt: Q70Z53 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70Z53 NP_660289.2 315 37584 S244 K K D C E E S S H K K S R L S
Chimpanzee Pan troglodytes XP_507931 315 37511 S244 K K D C E E S S H K K S R L S
Rhesus Macaque Macaca mulatta XP_001092952 315 37404 S244 K T D C G E S S R K K S R L S
Dog Lupus familis XP_534970 399 47063 S328 K T K K D E E S S H K K S R L
Cat Felis silvestris
Mouse Mus musculus Q8BP78 315 37243 P244 T P E C D E S P R K K S R S P
Rat Rattus norvegicus Q5FVF1 315 37100 P244 K T E S D E S P H K N S R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507589 346 40793 S275 E T N N E G L S L K K P R L S
Chicken Gallus gallus XP_421674 329 38511 K254 V G N S K Q P K I K K A K L S
Frog Xenopus laevis NP_001086932 322 38377 S248 K T E R E E S S R K K K K T S
Zebra Danio Brachydanio rerio NP_001006006 333 39156 K253 E N L D V S K K S K S S K S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122241 200 24077 F130 L K S W E V N F G Y I E H G Q
Nematode Worm Caenorhab. elegans NP_001129806 316 37238 W246 K K R A V R K W E K E R K R T
Sea Urchin Strong. purpuratus XP_782837 350 41331 R279 R S K H H K E R R H K K R R T
Poplar Tree Populus trichocarpa XP_002299940 243 28747 L173 C D R C A E K L H Y K R R K E
Maize Zea mays NP_001144502 172 20429 D102 F K E Y C I A D M T Q Y K K G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001154235 282 33712 S203 Q K R K R S K S H S E D D T D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.7 71.6 N.A. 86 86.9 N.A. 65.6 68.3 65.5 65.1 N.A. N.A. 41.9 39.5 48.2
Protein Similarity: 100 99.6 98 74.6 N.A. 93.6 94.2 N.A. 76.8 78.4 78.2 75.6 N.A. N.A. 50.1 57.9 64
P-Site Identity: 100 100 80 26.6 N.A. 46.6 53.3 N.A. 46.6 26.6 53.3 13.3 N.A. N.A. 13.3 20 13.3
P-Site Similarity: 100 100 80 33.3 N.A. 60 66.6 N.A. 60 60 66.6 26.6 N.A. N.A. 20 40 33.3
Percent
Protein Identity: 39.6 32 N.A. 39.6 N.A. N.A.
Protein Similarity: 54.2 41.5 N.A. 54.6 N.A. N.A.
P-Site Identity: 33.3 6.6 N.A. 20 N.A. N.A.
P-Site Similarity: 33.3 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 7 0 0 0 0 7 0 0 0 % A
% Cys: 7 0 0 32 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 19 7 19 0 0 7 0 0 0 7 7 0 7 % D
% Glu: 13 0 25 0 32 50 13 0 7 0 13 7 0 0 7 % E
% Phe: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 7 7 0 0 7 0 0 0 0 7 7 % G
% His: 0 0 0 7 7 0 0 0 32 13 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 7 0 0 0 0 % I
% Lys: 44 38 13 13 7 7 25 13 0 63 63 19 32 13 0 % K
% Leu: 7 0 7 0 0 0 7 7 7 0 0 0 0 32 7 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 13 7 0 0 7 0 0 0 7 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 7 13 0 0 0 7 0 0 7 % P
% Gln: 7 0 0 0 0 7 0 0 0 0 7 0 0 0 7 % Q
% Arg: 7 0 19 7 7 7 0 7 25 0 0 13 50 19 7 % R
% Ser: 0 7 7 13 0 13 38 44 13 7 7 38 7 19 44 % S
% Thr: 7 32 0 0 0 0 0 0 0 7 0 0 0 13 13 % T
% Val: 7 0 0 0 13 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 13 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _