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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRA10AC1
All Species:
19.09
Human Site:
S252
Identified Species:
28
UniProt:
Q70Z53
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70Z53
NP_660289.2
315
37584
S252
H
K
K
S
R
L
S
S
A
E
E
A
S
K
K
Chimpanzee
Pan troglodytes
XP_507931
315
37511
S252
H
K
K
S
R
L
S
S
A
E
E
A
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001092952
315
37404
S252
R
K
K
S
R
L
S
S
A
E
E
A
S
K
K
Dog
Lupus familis
XP_534970
399
47063
S336
S
H
K
K
S
R
L
S
S
A
E
E
T
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP78
315
37243
P252
R
K
K
S
R
S
P
P
S
E
E
A
S
K
G
Rat
Rattus norvegicus
Q5FVF1
315
37100
S252
H
K
N
S
R
S
S
S
S
E
E
A
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507589
346
40793
S283
L
K
K
P
R
L
S
S
S
R
K
K
S
S
K
Chicken
Gallus gallus
XP_421674
329
38511
H262
I
K
K
A
K
L
S
H
S
G
K
K
K
S
K
Frog
Xenopus laevis
NP_001086932
322
38377
H256
R
K
K
K
K
T
S
H
S
Q
K
N
T
N
T
Zebra Danio
Brachydanio rerio
NP_001006006
333
39156
K261
S
K
S
S
K
S
R
K
N
K
D
K
R
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122241
200
24077
K138
G
Y
I
E
H
G
Q
K
K
N
A
L
V
K
L
Nematode Worm
Caenorhab. elegans
NP_001129806
316
37238
K254
E
K
E
R
K
R
T
K
K
D
E
E
E
D
D
Sea Urchin
Strong. purpuratus
XP_782837
350
41331
S287
R
H
K
K
R
R
T
S
S
E
S
E
E
S
L
Poplar Tree
Populus trichocarpa
XP_002299940
243
28747
K181
H
Y
K
R
R
K
E
K
E
Q
I
E
K
R
E
Maize
Zea mays
NP_001144502
172
20429
K110
M
T
Q
Y
K
K
G
K
I
G
L
R
W
R
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001154235
282
33712
E211
H
S
E
D
D
T
D
E
E
E
K
R
K
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.7
71.6
N.A.
86
86.9
N.A.
65.6
68.3
65.5
65.1
N.A.
N.A.
41.9
39.5
48.2
Protein Similarity:
100
99.6
98
74.6
N.A.
93.6
94.2
N.A.
76.8
78.4
78.2
75.6
N.A.
N.A.
50.1
57.9
64
P-Site Identity:
100
100
93.3
26.6
N.A.
60
66.6
N.A.
53.3
33.3
20
20
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
100
100
93.3
40
N.A.
66.6
80
N.A.
66.6
60
53.3
40
N.A.
N.A.
6.6
40
40
Percent
Protein Identity:
39.6
32
N.A.
39.6
N.A.
N.A.
Protein Similarity:
54.2
41.5
N.A.
54.6
N.A.
N.A.
P-Site Identity:
20
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
40
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
19
7
7
32
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
7
0
0
7
7
0
0
7
7
% D
% Glu:
7
0
13
7
0
0
7
7
13
44
44
25
13
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
7
7
0
0
13
0
0
0
0
19
% G
% His:
32
13
0
0
7
0
0
13
0
0
0
0
0
0
7
% H
% Ile:
7
0
7
0
0
0
0
0
7
0
7
0
0
0
0
% I
% Lys:
0
63
63
19
32
13
0
32
13
7
25
19
19
38
38
% K
% Leu:
7
0
0
0
0
32
7
0
0
0
7
7
0
0
13
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
7
0
7
0
7
0
% N
% Pro:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
7
0
0
13
0
0
0
7
0
% Q
% Arg:
25
0
0
13
50
19
7
0
0
7
0
13
7
13
0
% R
% Ser:
13
7
7
38
7
19
44
44
44
0
7
0
38
25
0
% S
% Thr:
0
7
0
0
0
13
13
0
0
0
0
0
13
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
13
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _