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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRA10AC1
All Species:
19.09
Human Site:
S270
Identified Species:
28
UniProt:
Q70Z53
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70Z53
NP_660289.2
315
37584
S270
G
H
S
S
S
K
K
S
E
D
S
L
L
R
N
Chimpanzee
Pan troglodytes
XP_507931
315
37511
S270
G
H
S
S
S
K
K
S
E
D
S
L
L
R
N
Rhesus Macaque
Macaca mulatta
XP_001092952
315
37404
S270
G
H
S
S
S
K
K
S
E
D
S
L
K
R
N
Dog
Lupus familis
XP_534970
399
47063
K354
K
G
H
S
S
S
K
K
S
E
S
C
V
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP78
315
37243
S270
G
H
S
S
S
K
K
S
E
D
S
R
N
R
N
Rat
Rattus norvegicus
Q5FVF1
315
37100
S270
G
H
S
S
S
K
R
S
E
D
S
R
N
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507589
346
40793
P301
D
R
A
D
T
K
K
P
E
A
G
V
I
N
S
Chicken
Gallus gallus
XP_421674
329
38511
E280
H
G
D
Q
V
S
S
E
D
S
D
T
S
D
K
Frog
Xenopus laevis
NP_001086932
322
38377
S274
P
T
E
K
H
T
N
S
S
E
T
D
S
S
D
Zebra Danio
Brachydanio rerio
NP_001006006
333
39156
S279
R
K
E
H
S
S
S
S
S
E
E
S
Q
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122241
200
24077
N156
P
E
C
S
I
K
L
N
Y
R
S
Q
K
R
E
Nematode Worm
Caenorhab. elegans
NP_001129806
316
37238
N272
L
N
Q
H
E
A
K
N
Q
E
T
K
V
Q
P
Sea Urchin
Strong. purpuratus
XP_782837
350
41331
K305
D
D
Q
G
E
K
K
K
T
K
H
R
S
K
D
Poplar Tree
Populus trichocarpa
XP_002299940
243
28747
L199
R
I
R
K
R
E
L
L
E
V
V
D
D
L
D
Maize
Zea mays
NP_001144502
172
20429
F128
V
I
S
G
K
G
Q
F
I
C
G
N
R
H
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001154235
282
33712
Q229
E
S
N
E
K
K
K
Q
K
R
N
R
S
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.7
71.6
N.A.
86
86.9
N.A.
65.6
68.3
65.5
65.1
N.A.
N.A.
41.9
39.5
48.2
Protein Similarity:
100
99.6
98
74.6
N.A.
93.6
94.2
N.A.
76.8
78.4
78.2
75.6
N.A.
N.A.
50.1
57.9
64
P-Site Identity:
100
100
93.3
26.6
N.A.
86.6
80
N.A.
20
0
6.6
13.3
N.A.
N.A.
26.6
6.6
13.3
P-Site Similarity:
100
100
93.3
40
N.A.
86.6
86.6
N.A.
53.3
6.6
26.6
26.6
N.A.
N.A.
33.3
53.3
26.6
Percent
Protein Identity:
39.6
32
N.A.
39.6
N.A.
N.A.
Protein Similarity:
54.2
41.5
N.A.
54.6
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
7
0
0
7
% C
% Asp:
13
7
7
7
0
0
0
0
7
32
7
13
7
7
19
% D
% Glu:
7
7
13
7
13
7
0
7
44
25
7
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
32
13
0
13
0
7
0
0
0
0
13
0
0
0
0
% G
% His:
7
32
7
13
7
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
0
13
0
0
7
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
7
7
0
13
13
57
57
13
7
7
0
7
13
7
7
% K
% Leu:
7
0
0
0
0
0
13
7
0
0
0
19
13
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
7
13
0
0
7
7
13
13
32
% N
% Pro:
13
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
0
0
13
7
0
0
7
7
7
0
0
7
7
13
0
% Q
% Arg:
13
7
7
0
7
0
7
0
0
13
0
25
7
38
7
% R
% Ser:
0
7
38
44
44
19
13
44
19
7
44
7
25
7
19
% S
% Thr:
0
7
0
0
7
7
0
0
7
0
13
7
0
0
0
% T
% Val:
7
0
0
0
7
0
0
0
0
7
7
7
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _