KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRA10AC1
All Species:
25.15
Human Site:
S273
Identified Species:
36.89
UniProt:
Q70Z53
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70Z53
NP_660289.2
315
37584
S273
S
S
K
K
S
E
D
S
L
L
R
N
S
D
E
Chimpanzee
Pan troglodytes
XP_507931
315
37511
S273
S
S
K
K
S
E
D
S
L
L
R
N
S
D
E
Rhesus Macaque
Macaca mulatta
XP_001092952
315
37404
S273
S
S
K
K
S
E
D
S
L
K
R
N
S
D
E
Dog
Lupus familis
XP_534970
399
47063
S357
S
S
S
K
K
S
E
S
C
V
N
R
N
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP78
315
37243
S273
S
S
K
K
S
E
D
S
R
N
R
N
A
E
E
Rat
Rattus norvegicus
Q5FVF1
315
37100
S273
S
S
K
R
S
E
D
S
R
N
R
N
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507589
346
40793
G304
D
T
K
K
P
E
A
G
V
I
N
S
S
D
E
Chicken
Gallus gallus
XP_421674
329
38511
D283
Q
V
S
S
E
D
S
D
T
S
D
K
D
S
D
Frog
Xenopus laevis
NP_001086932
322
38377
T277
K
H
T
N
S
S
E
T
D
S
S
D
T
D
G
Zebra Danio
Brachydanio rerio
NP_001006006
333
39156
E282
H
S
S
S
S
S
E
E
S
Q
E
S
D
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122241
200
24077
S159
S
I
K
L
N
Y
R
S
Q
K
R
E
A
K
K
Nematode Worm
Caenorhab. elegans
NP_001129806
316
37238
T275
H
E
A
K
N
Q
E
T
K
V
Q
P
S
T
S
Sea Urchin
Strong. purpuratus
XP_782837
350
41331
H308
G
E
K
K
K
T
K
H
R
S
K
D
E
G
E
Poplar Tree
Populus trichocarpa
XP_002299940
243
28747
V202
K
R
E
L
L
E
V
V
D
D
L
D
N
E
G
Maize
Zea mays
NP_001144502
172
20429
G131
G
K
G
Q
F
I
C
G
N
R
H
C
D
E
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001154235
282
33712
N232
E
K
K
K
Q
K
R
N
R
S
Q
S
H
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.7
71.6
N.A.
86
86.9
N.A.
65.6
68.3
65.5
65.1
N.A.
N.A.
41.9
39.5
48.2
Protein Similarity:
100
99.6
98
74.6
N.A.
93.6
94.2
N.A.
76.8
78.4
78.2
75.6
N.A.
N.A.
50.1
57.9
64
P-Site Identity:
100
100
93.3
26.6
N.A.
73.3
66.6
N.A.
40
0
13.3
13.3
N.A.
N.A.
26.6
13.3
20
P-Site Similarity:
100
100
93.3
53.3
N.A.
86.6
80
N.A.
66.6
13.3
40
26.6
N.A.
N.A.
46.6
53.3
33.3
Percent
Protein Identity:
39.6
32
N.A.
39.6
N.A.
N.A.
Protein Similarity:
54.2
41.5
N.A.
54.6
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
20
N.A.
N.A.
P-Site Similarity:
33.3
20
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
7
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
0
7
32
7
13
7
7
19
19
32
13
% D
% Glu:
7
13
7
0
7
44
25
7
0
0
7
7
7
19
50
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
7
0
0
0
0
13
0
0
0
0
0
13
19
% G
% His:
13
7
0
0
0
0
0
7
0
0
7
0
7
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
13
13
57
57
13
7
7
0
7
13
7
7
0
13
13
% K
% Leu:
0
0
0
13
7
0
0
0
19
13
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
13
0
0
7
7
13
13
32
13
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
0
0
7
7
7
0
0
7
7
13
0
0
0
0
% Q
% Arg:
0
7
0
7
0
0
13
0
25
7
38
7
0
0
0
% R
% Ser:
44
44
19
13
44
19
7
44
7
25
7
19
32
19
7
% S
% Thr:
0
7
7
0
0
7
0
13
7
0
0
0
7
7
0
% T
% Val:
0
7
0
0
0
0
7
7
7
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _