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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRA10AC1 All Species: 27.27
Human Site: T27 Identified Species: 40
UniProt: Q70Z53 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70Z53 NP_660289.2 315 37584 T27 S S K R K K R T V E D D L L L
Chimpanzee Pan troglodytes XP_507931 315 37511 T27 S S K R K K R T V E D D L L L
Rhesus Macaque Macaca mulatta XP_001092952 315 37404 T27 S S K R K T R T V E D D L L L
Dog Lupus familis XP_534970 399 47063 T113 S N K R K K R T I E D D L L L
Cat Felis silvestris
Mouse Mus musculus Q8BP78 315 37243 T27 S S K K R K K T V E D E L L L
Rat Rattus norvegicus Q5FVF1 315 37100 T27 S S K K R K K T V E D E L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507589 346 40793 A53 S G R G K K R A S S E E L L L
Chicken Gallus gallus XP_421674 329 38511 T38 S V Q K T K S T K E D S L L V
Frog Xenopus laevis NP_001086932 322 38377 L31 K D A D R S R L K K D E A L L
Zebra Danio Brachydanio rerio NP_001006006 333 39156 A37 S K D G E N R A G Q D E L L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122241 200 24077
Nematode Worm Caenorhab. elegans NP_001129806 316 37238 K33 S S S K P K R K G D F L N K D
Sea Urchin Strong. purpuratus XP_782837 350 41331 T32 R S R Q D L A T K P D Q S R V
Poplar Tree Populus trichocarpa XP_002299940 243 28747
Maize Zea mays NP_001144502 172 20429
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001154235 282 33712 A27 R V C R Q Y Q A H I R G L N A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.7 71.6 N.A. 86 86.9 N.A. 65.6 68.3 65.5 65.1 N.A. N.A. 41.9 39.5 48.2
Protein Similarity: 100 99.6 98 74.6 N.A. 93.6 94.2 N.A. 76.8 78.4 78.2 75.6 N.A. N.A. 50.1 57.9 64
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 73.3 N.A. 46.6 46.6 26.6 33.3 N.A. N.A. 0 26.6 20
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 66.6 66.6 46.6 53.3 N.A. N.A. 0 40 40
Percent
Protein Identity: 39.6 32 N.A. 39.6 N.A. N.A.
Protein Similarity: 54.2 41.5 N.A. 54.6 N.A. N.A.
P-Site Identity: 0 0 N.A. 13.3 N.A. N.A.
P-Site Similarity: 0 0 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 19 0 0 0 0 7 0 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 7 0 0 0 0 7 63 25 0 0 7 % D
% Glu: 0 0 0 0 7 0 0 0 0 44 7 32 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 0 13 0 0 0 0 13 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % I
% Lys: 7 7 38 25 32 50 13 7 19 7 0 0 0 7 0 % K
% Leu: 0 0 0 0 0 7 0 7 0 0 0 7 63 63 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 0 0 0 0 0 7 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 7 7 7 0 7 0 0 7 0 7 0 0 7 % Q
% Arg: 13 0 13 32 19 0 50 0 0 0 7 0 0 7 0 % R
% Ser: 63 44 7 0 0 7 7 0 7 7 0 7 7 0 0 % S
% Thr: 0 0 0 0 7 7 0 50 0 0 0 0 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 32 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _