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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRA10AC1 All Species: 47.88
Human Site: Y195 Identified Species: 70.22
UniProt: Q70Z53 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q70Z53 NP_660289.2 315 37584 Y195 S W E V N F G Y I E H G E K R
Chimpanzee Pan troglodytes XP_507931 315 37511 Y195 S W E V N F G Y I E H G E K R
Rhesus Macaque Macaca mulatta XP_001092952 315 37404 Y195 S W E V N F G Y V E H G E K R
Dog Lupus familis XP_534970 399 47063 Y281 S W E V N F G Y I E H G E K R
Cat Felis silvestris
Mouse Mus musculus Q8BP78 315 37243 Y195 S W E V N F G Y T E H G E K R
Rat Rattus norvegicus Q5FVF1 315 37100 Y195 S W E V N F G Y T E H G E K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507589 346 40793 Y228 S W E V N F G Y I E H G E K R
Chicken Gallus gallus XP_421674 329 38511 Y205 S W E V N F G Y V E H G E K R
Frog Xenopus laevis NP_001086932 322 38377 Y199 S W E V N F G Y E E H G E K R
Zebra Danio Brachydanio rerio NP_001006006 333 39156 Y204 S W E V N F A Y V E Q G E K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122241 200 24077 T86 E Y C I A D L T Y Y K Q N K V
Nematode Worm Caenorhab. elegans NP_001129806 316 37238 F202 L S S W E V N F T Y K E D N R
Sea Urchin Strong. purpuratus XP_782837 350 41331 Y194 T W E V N F A Y M E H G E K R
Poplar Tree Populus trichocarpa XP_002299940 243 28747 I129 I S G K G Q F I C G N K H C D
Maize Zea mays NP_001144502 172 20429 K58 V D S S L P I K T D K D T L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001154235 282 33712 Y154 S Y E V N F S Y H E A G E D K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.7 71.6 N.A. 86 86.9 N.A. 65.6 68.3 65.5 65.1 N.A. N.A. 41.9 39.5 48.2
Protein Similarity: 100 99.6 98 74.6 N.A. 93.6 94.2 N.A. 76.8 78.4 78.2 75.6 N.A. N.A. 50.1 57.9 64
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 100 93.3 93.3 80 N.A. N.A. 6.6 6.6 80
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 100 93.3 86.6 N.A. N.A. 20 20 93.3
Percent
Protein Identity: 39.6 32 N.A. 39.6 N.A. N.A.
Protein Similarity: 54.2 41.5 N.A. 54.6 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 60 N.A. N.A.
P-Site Similarity: 6.6 13.3 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 13 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 7 0 0 0 0 7 0 % C
% Asp: 0 7 0 0 0 7 0 0 0 7 0 7 7 7 7 % D
% Glu: 7 0 75 0 7 0 0 0 7 75 0 7 75 0 0 % E
% Phe: 0 0 0 0 0 75 7 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 7 0 57 0 0 7 0 75 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 63 0 7 0 0 % H
% Ile: 7 0 0 7 0 0 7 7 25 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 19 7 0 75 7 % K
% Leu: 7 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 75 0 7 0 0 0 7 0 7 7 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 7 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 % R
% Ser: 69 13 13 7 0 0 7 0 0 0 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 7 25 0 0 0 7 0 0 % T
% Val: 7 0 0 75 0 7 0 0 19 0 0 0 0 0 7 % V
% Trp: 0 69 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 0 0 0 75 7 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _