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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD1
All Species:
22.42
Human Site:
S137
Identified Species:
41.11
UniProt:
Q719H9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q719H9
NP_001129677.1
257
29405
S137
D
R
E
T
G
R
F
S
R
P
C
E
C
L
V
Chimpanzee
Pan troglodytes
XP_512072
825
91781
S705
D
R
E
T
G
R
F
S
R
P
C
E
C
L
V
Rhesus Macaque
Macaca mulatta
XP_001089277
283
31894
S163
E
Q
E
Q
R
R
R
S
R
A
C
D
C
L
V
Dog
Lupus familis
XP_537294
1243
134875
S1123
D
R
E
T
G
R
F
S
R
P
C
E
C
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0E1
283
31868
S163
D
Q
E
Q
R
R
R
S
R
A
C
D
C
L
V
Rat
Rattus norvegicus
Q8R4G8
257
29416
S137
D
R
E
T
S
R
F
S
R
P
C
E
C
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509914
290
33065
F170
E
K
E
Q
R
K
H
F
Q
P
C
D
C
L
V
Chicken
Gallus gallus
Q5ZJP7
289
33209
R153
P
L
K
G
E
K
V
R
Q
A
F
L
G
L
M
Frog
Xenopus laevis
Q6DCX3
255
29156
F137
D
K
E
H
R
K
H
F
Q
P
C
D
C
L
V
Zebra Danio
Brachydanio rerio
Q6DC02
257
29292
A137
E
R
E
Q
R
R
L
A
N
P
C
D
C
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611588
338
36838
N210
M
R
K
D
R
V
R
N
G
N
Y
L
V
A
P
Honey Bee
Apis mellifera
XP_394688
316
34359
T166
E
R
I
K
N
G
S
T
G
T
T
T
M
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785600
295
32656
S168
M
K
S
S
E
E
S
S
K
T
T
Q
E
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
72.7
20.6
N.A.
73.1
99.6
N.A.
70.6
23.8
78.2
78.5
N.A.
42.3
47.7
N.A.
49.1
Protein Similarity:
100
31.1
80.9
20.6
N.A.
80.5
99.6
N.A.
78.6
39.7
87.9
87.1
N.A.
52.3
58.8
N.A.
63.7
P-Site Identity:
100
100
53.3
100
N.A.
60
93.3
N.A.
40
6.6
46.6
53.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
73.3
100
N.A.
73.3
93.3
N.A.
73.3
33.3
73.3
73.3
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
24
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
70
0
70
0
0
% C
% Asp:
47
0
0
8
0
0
0
0
0
0
0
39
0
0
0
% D
% Glu:
31
0
70
0
16
8
0
0
0
0
0
31
8
0
0
% E
% Phe:
0
0
0
0
0
0
31
16
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
24
8
0
0
16
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
24
16
8
0
24
0
0
8
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
8
0
0
0
0
16
0
77
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
54
0
0
0
0
8
% P
% Gln:
0
16
0
31
0
0
0
0
24
0
0
8
0
0
0
% Q
% Arg:
0
54
0
0
47
54
24
8
47
0
0
0
0
0
8
% R
% Ser:
0
0
8
8
8
0
16
54
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
31
0
0
0
8
0
16
16
8
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _