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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD1
All Species:
36.36
Human Site:
S228
Identified Species:
66.67
UniProt:
Q719H9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q719H9
NP_001129677.1
257
29405
S228
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Chimpanzee
Pan troglodytes
XP_512072
825
91781
S796
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Rhesus Macaque
Macaca mulatta
XP_001089277
283
31894
S254
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Dog
Lupus familis
XP_537294
1243
134875
S1214
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0E1
283
31868
S254
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Rat
Rattus norvegicus
Q8R4G8
257
29416
S228
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509914
290
33065
S261
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
M
Chicken
Gallus gallus
Q5ZJP7
289
33209
R255
I
V
T
D
L
S
D
R
G
I
T
V
D
H
Q
Frog
Xenopus laevis
Q6DCX3
255
29156
S228
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Zebra Danio
Brachydanio rerio
Q6DC02
257
29292
S228
C
G
G
G
V
D
S
S
Q
F
S
E
Y
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611588
338
36838
K301
F
P
L
N
G
Y
C
K
L
N
S
V
Q
V
L
Honey Bee
Apis mellifera
XP_394688
316
34359
Q258
R
S
G
V
A
W
H
Q
Q
D
A
R
H
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785600
295
32656
V256
G
F
C
K
M
N
T
V
Q
V
L
Q
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
72.7
20.6
N.A.
73.1
99.6
N.A.
70.6
23.8
78.2
78.5
N.A.
42.3
47.7
N.A.
49.1
Protein Similarity:
100
31.1
80.9
20.6
N.A.
80.5
99.6
N.A.
78.6
39.7
87.9
87.1
N.A.
52.3
58.8
N.A.
63.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
0
100
100
N.A.
20
20
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
100
100
N.A.
20
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
70
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
70
8
0
0
8
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
70
0
0
0
0
0
% F
% Gly:
8
70
77
70
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
8
0
0
0
8
0
8
0
0
8
77
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
85
0
0
8
8
0
8
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
0
8
0
0
0
8
70
70
0
0
77
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
0
8
0
8
70
0
0
8
0
8
0
16
0
85
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _