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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD1
All Species:
27.58
Human Site:
S247
Identified Species:
50.56
UniProt:
Q719H9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q719H9
NP_001129677.1
257
29405
S247
R
R
T
P
R
V
P
S
V
I
R
I
K
Q
E
Chimpanzee
Pan troglodytes
XP_512072
825
91781
S815
R
R
T
P
R
V
P
S
V
I
R
I
K
Q
E
Rhesus Macaque
Macaca mulatta
XP_001089277
283
31894
T273
R
R
P
Q
P
A
P
T
A
V
R
I
K
Q
E
Dog
Lupus familis
XP_537294
1243
134875
S1233
R
R
T
P
R
V
P
S
V
I
R
I
K
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0E1
283
31868
T273
R
R
P
Q
P
T
P
T
A
V
R
I
K
Q
E
Rat
Rattus norvegicus
Q8R4G8
257
29416
S247
R
R
T
P
R
V
P
S
V
I
R
I
K
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509914
290
33065
T280
R
R
L
Q
P
A
P
T
T
I
R
I
K
Q
E
Chicken
Gallus gallus
Q5ZJP7
289
33209
H274
C
D
K
H
L
I
N
H
Y
Y
C
K
R
P
I
Frog
Xenopus laevis
Q6DCX3
255
29156
M247
R
R
M
Q
P
N
T
M
R
I
K
Q
E
P
L
Zebra Danio
Brachydanio rerio
Q6DC02
257
29292
T247
R
R
S
H
N
T
N
T
P
I
R
I
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611588
338
36838
A320
N
A
G
F
T
I
E
A
S
V
G
G
Q
Q
F
Honey Bee
Apis mellifera
XP_394688
316
34359
S277
N
G
Y
C
K
L
N
S
V
Q
A
I
T
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785600
295
32656
G275
G
V
I
A
S
S
G
G
G
I
E
G
S
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
72.7
20.6
N.A.
73.1
99.6
N.A.
70.6
23.8
78.2
78.5
N.A.
42.3
47.7
N.A.
49.1
Protein Similarity:
100
31.1
80.9
20.6
N.A.
80.5
99.6
N.A.
78.6
39.7
87.9
87.1
N.A.
52.3
58.8
N.A.
63.7
P-Site Identity:
100
100
53.3
100
N.A.
53.3
100
N.A.
60
0
20
53.3
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
66.6
100
N.A.
66.6
100
N.A.
66.6
13.3
33.3
66.6
N.A.
33.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
16
0
8
16
0
8
0
0
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
62
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
8
8
8
0
0
0
8
8
8
0
8
16
0
0
0
% G
% His:
0
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
16
0
0
0
62
0
70
0
0
8
% I
% Lys:
0
0
8
0
8
0
0
0
0
0
8
8
62
0
0
% K
% Leu:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
8
8
24
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
31
31
0
54
0
8
0
0
0
0
16
0
% P
% Gln:
0
0
0
31
0
0
0
0
0
8
0
8
8
77
0
% Q
% Arg:
70
70
0
0
31
0
0
0
8
0
62
0
8
8
0
% R
% Ser:
0
0
8
0
8
8
0
39
8
0
0
0
8
0
0
% S
% Thr:
0
0
31
0
8
16
8
31
8
0
0
0
8
0
0
% T
% Val:
0
8
0
0
0
31
0
0
39
24
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _