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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMUB2 All Species: 12.12
Human Site: S259 Identified Species: 26.67
UniProt: Q71RG4 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71RG4 NP_001070142.1 321 33788 S259 P S A S L A P S A T E P P S L
Chimpanzee Pan troglodytes XP_001140790 275 29043 A214 S A S L A P S A T E P P S L G
Rhesus Macaque Macaca mulatta XP_001114374 321 33798 S259 P S A S L A P S A T E P P S L
Dog Lupus familis XP_848737 302 31674 S239 P S A S L A P S S A T E P P S
Cat Felis silvestris
Mouse Mus musculus Q3V209 319 33790 T258 P S A S L T P T T E Q S S L G
Rat Rattus norvegicus Q4FZV7 319 34004 T258 P S T S L T P T T E Q S S L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519661 275 27900 N214 R S L H V T D N C V I H C Q R
Chicken Gallus gallus XP_428658 149 16707 A87 P A P A G P R A S A D P V H T
Frog Xenopus laevis Q3KPV4 308 33137 V246 Q H A S V P G V G A D Q A N V
Zebra Danio Brachydanio rerio Q6P135 292 31060 A231 A M P A G A R A A D Q V H V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34256 616 70122 R468 N V T T A R R R A A Q D R N V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 98.1 89 N.A. 85.6 85.9 N.A. 51.4 24.6 28 42.3 N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: 100 85.6 98.4 90.6 N.A. 88.7 89 N.A. 59.5 33.9 43.2 55.4 N.A. N.A. N.A. 31.8 N.A.
P-Site Identity: 100 6.6 100 60 N.A. 40 33.3 N.A. 6.6 13.3 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 100 66.6 N.A. 53.3 46.6 N.A. 20 46.6 40 33.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 46 19 19 37 0 28 37 37 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 10 19 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 28 19 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 19 0 10 0 10 0 0 0 0 0 28 % G
% His: 0 10 0 10 0 0 0 0 0 0 0 10 10 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 10 46 0 0 0 0 0 0 0 0 28 19 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 10 0 0 0 0 0 19 0 % N
% Pro: 55 0 19 0 0 28 46 0 0 0 10 37 28 10 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 37 10 0 10 0 % Q
% Arg: 10 0 0 0 0 10 28 10 0 0 0 0 10 0 10 % R
% Ser: 10 55 10 55 0 0 10 28 19 0 0 19 28 19 10 % S
% Thr: 0 0 19 10 0 28 0 19 28 19 10 0 0 0 10 % T
% Val: 0 10 0 0 19 0 0 10 0 10 0 10 10 10 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _