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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMUB2 All Species: 4.55
Human Site: S265 Identified Species: 10
UniProt: Q71RG4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71RG4 NP_001070142.1 321 33788 S265 P S A T E P P S L G V N V G S
Chimpanzee Pan troglodytes XP_001140790 275 29043 L220 S A T E P P S L G V N V G S L
Rhesus Macaque Macaca mulatta XP_001114374 321 33798 S265 P S A T E P P S L G V N V G S
Dog Lupus familis XP_848737 302 31674 P245 P S S A T E P P S L G V S V G
Cat Felis silvestris
Mouse Mus musculus Q3V209 319 33790 L264 P T T E Q S S L G V N V G S L
Rat Rattus norvegicus Q4FZV7 319 34004 L264 P T T E Q S S L G V N V G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519661 275 27900 Q220 D N C V I H C Q R G P A P A P
Chicken Gallus gallus XP_428658 149 16707 H93 R A S A D P V H T A L N V G S
Frog Xenopus laevis Q3KPV4 308 33137 N252 G V G A D Q A N V P L N V G N
Zebra Danio Brachydanio rerio Q6P135 292 31060 V237 R A A D Q V H V A L N V G S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34256 616 70122 N474 R R A A Q D R N V G Q I Y L L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 98.1 89 N.A. 85.6 85.9 N.A. 51.4 24.6 28 42.3 N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: 100 85.6 98.4 90.6 N.A. 88.7 89 N.A. 59.5 33.9 43.2 55.4 N.A. N.A. N.A. 31.8 N.A.
P-Site Identity: 100 6.6 100 20 N.A. 6.6 6.6 N.A. 6.6 33.3 20 6.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 100 26.6 N.A. 20 20 N.A. 13.3 60 53.3 20 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 37 37 0 0 10 0 10 10 0 10 0 10 0 % A
% Cys: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 19 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 28 19 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 28 37 10 0 37 37 10 % G
% His: 0 0 0 0 0 10 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 28 19 19 19 0 0 10 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 19 0 0 37 37 0 0 10 % N
% Pro: 46 0 0 0 10 37 28 10 0 10 10 0 10 0 10 % P
% Gln: 0 0 0 0 37 10 0 10 0 0 10 0 0 0 0 % Q
% Arg: 28 10 0 0 0 0 10 0 10 0 0 0 0 0 0 % R
% Ser: 10 28 19 0 0 19 28 19 10 0 0 0 10 37 28 % S
% Thr: 0 19 28 19 10 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 10 0 10 0 10 10 10 19 28 19 46 37 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _