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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A5
All Species:
26.97
Human Site:
S273
Identified Species:
45.64
UniProt:
Q71RS6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71RS6
NP_995322.1
500
54888
S273
S
G
I
F
Y
E
D
S
G
Y
S
Q
L
S
I
Chimpanzee
Pan troglodytes
XP_510380
500
54850
S273
S
G
I
F
Y
E
D
S
G
Y
S
Q
L
S
I
Rhesus Macaque
Macaca mulatta
XP_001112601
500
55038
S273
S
G
I
F
Y
E
D
S
G
Y
S
Q
L
S
I
Dog
Lupus familis
XP_851849
501
55168
S274
S
G
I
F
Y
E
E
S
G
Y
S
Q
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C261
501
54965
S274
S
G
I
F
Q
E
D
S
G
Y
S
Q
L
S
L
Rat
Rattus norvegicus
Q9EPQ0
624
69371
T316
A
G
L
R
I
M
I
T
S
H
F
P
P
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517974
336
36438
P129
H
E
V
S
E
D
P
P
S
V
F
S
V
P
E
Chicken
Gallus gallus
Q9IAL7
651
72677
M344
A
S
L
H
N
S
L
M
R
N
S
I
F
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
S286
S
G
I
F
Q
D
D
S
G
Y
S
H
L
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN12
642
70657
P397
S
V
V
T
G
D
G
P
P
A
A
V
K
S
G
Honey Bee
Apis mellifera
XP_624828
470
51842
W265
V
W
P
A
R
A
G
W
I
R
K
T
A
W
I
Nematode Worm
Caenorhab. elegans
P34315
590
66151
K321
R
G
V
V
H
D
F
K
E
H
L
K
P
W
P
Sea Urchin
Strong. purpuratus
XP_780438
570
63240
T327
S
G
G
K
F
P
T
T
Y
T
H
R
P
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI2
643
70138
T390
S
S
S
C
T
K
F
T
S
L
L
E
I
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.8
90.4
N.A.
84.6
34.7
N.A.
46.7
31.6
N.A.
66.4
N.A.
34.7
37.2
23.2
37.7
Protein Similarity:
100
99.5
96.4
94.8
N.A.
92.2
51.9
N.A.
55.4
48.6
N.A.
81.2
N.A.
51.5
59.2
40.5
55.9
P-Site Identity:
100
100
100
80
N.A.
86.6
6.6
N.A.
0
6.6
N.A.
73.3
N.A.
13.3
6.6
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
20
26.6
N.A.
86.6
N.A.
33.3
6.6
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
8
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
29
36
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
36
8
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
43
8
0
15
0
0
0
15
0
8
0
0
% F
% Gly:
0
65
8
0
8
0
15
0
43
0
0
0
0
0
8
% G
% His:
8
0
0
8
8
0
0
0
0
15
8
8
0
0
0
% H
% Ile:
0
0
43
0
8
0
8
0
8
0
0
8
8
0
29
% I
% Lys:
0
0
0
8
0
8
0
8
0
0
8
8
8
8
0
% K
% Leu:
0
0
15
0
0
0
8
0
0
8
15
0
43
0
43
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
8
15
8
0
0
8
22
22
8
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
36
0
8
0
% Q
% Arg:
8
0
0
8
8
0
0
0
8
8
0
8
0
0
0
% R
% Ser:
65
15
8
8
0
8
0
43
22
0
50
8
0
50
0
% S
% Thr:
0
0
0
8
8
0
8
22
0
8
0
8
0
0
8
% T
% Val:
8
8
22
8
0
0
0
0
0
8
0
8
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
8
0
0
0
0
0
15
0
% W
% Tyr:
0
0
0
0
29
0
0
0
8
43
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _